| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Androgen Receptor |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the Androgen Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This Androgen Receptor antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P10275 |
| Purity: |
Antigen affinity |
| Description: |
Androgen receptor functions as a steroid-hormone activated transcription factor, DNA-binding domain, Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease), Mutations in this gene are also associated with complete androgen insensitivity (CAIS), This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein, Two alternatively spliced variants encoding distinct isoforms have been described, Upon binding the hormone ligand, and androgen-binding domain, and then stimulates transcription of androgen responsive genes, dimerizes, the receptor dissociates from accessory proteins, translocates into the nucleus, The AR gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human Androgen Receptor (LKNQKFFDELRMNYIKE) was used as the immunogen for this Androgen Receptor antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Androgen Receptor antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Androgen Receptor |
| Short name: |
Androgen Receptor Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Androgen Receptor (Antibody to) |
| Alternative technique: |
antibodies |