| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PPID |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the PPID antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This PPID antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q08752 |
| Purity: |
Antigen affinity |
| Description: |
By fluorescence in situ hybridization, PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins, Peptidylprolyl isomerase D, The gene contains 10 exons and spans 14, The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase(PPIase) family, This protein has been shown to possess PPIase activity and, also known as PPID, can bind to the immunosuppressant ciclosporin, is an enzyme which in humans is encoded by the PPID gene, similar to other family members, the PPID gene is mapped to chromosome 4q31, 2 kb of genomic DNA, 3, Cyclophilin D |
| Immunogen: |
Amino acids 351-370 (KQKIKAQKDKEKAVYAKMFA-human) were used as the immunogen for this PPID antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PPID antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PPID |
| Short name: |
PPID Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
peptidylprolyl isomerase D (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CYP-40 and CYPD, Hsp90 protein binding, PPID and IDBG-43002 and ENSG00000171497 and 5481, PPID and IDBG-630512 and ENSBTAG00000016680 and 281420, Ppid and IDBG-153114 and ENSMUSG00000027804 and 67738, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000413 and protein peptidyl-prolyl isomerization and biological process this GO :0003755 and peptidyl-prolyl cis-trans isomerase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006457 and protein folding and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0015031 and protein transport and biological process this GO :0016018 and cyclosporin A binding and molecular function this GO :0019076 and viral release from host cell and biological process this GO :0030331 and estrogen receptor binding and molecular function this GO :0030544 and Hsp70 protein binding and molecular function this GO :0031072 and heat shock protein binding and molecular function this GO :0034389 and lipid particle organization and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045070 and positive regulation of viral genome replication and biological process this GO :0050714 and positive regulation of protein secretion and biological process this GO :0051879 and Hsp90 protein binding and molecular function this GO :0061077 and chaperone-mediated protein folding and biological process this GO :0071492 and cellular response to UV-A and biological process, this GO :0003755 : peptidyl-prolyl cis-trans isomerase activity, this GO :0003755 : peptidyl-prolyl cis-trans isomerase activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0016018 : cyclosporin A binding and also this GO :0030331 : estrogen receptor binding and also this GO :0030544 : Hsp70 protein binding and also this GO :0031072 : heat shock protein binding and also this GO :0051879 : Hsp90 protein binding, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0016018 : cyclosporin A binding, this GO :0030331 : estrogen receptor binding, this GO :0030544 : Hsp70 protein binding, this GO :0031072 : heat shock protein binding, this GO :0051879 : Hsp90 protein binding, peptidylprolyl isomerase D |
| Identity: |
9257 |
| Gene: |
PPID |
More about : PPID |
| Long gene name: |
peptidylprolyl isomerase D |
| Synonyms gene name: |
peptidylprolyl isomerase D (cyclophilin D) |
| Synonyms: |
CYP-40 |
| Synonyms name: |
cyclophilin 40 |
| Locus: |
4q32, 1 |
| Discovery year: |
1995-08-23 |
| Entrez gene record: |
5481 |
| Pubmed identfication: |
8509368 |
| RefSeq identity: |
NM_005038 |
| Classification: |
Tetratricopeptide repeat domain containing Cyclophilin peptidylprolyl isomerases |
| Havana BLAST/BLAT: |
OTTHUMG00000161927 |