| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CXCL13 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the CXCL13 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This CXCL13 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O43927 |
| Purity: |
Antigen affinity |
| Description: |
It is expressed highly in the liver, Its gene is mapped to human chromosome 4 in a cluster of other CXC chemokines, The protein induces chemotaxis of BLR1-expressing B cells, The protein is a small cytokine belonging to the CXC chemokine family, lymph nodes and gut of humans, spleen, C-X-C motif chemokine 13 also known as B lymphocyte chemoattractant(BLC) is a protein that in humans is encoded by the CXCL13 gene |
| Immunogen: |
An amino acid sequence from the C-terminus of human CXCL13 (DPQAEWIQRMMEVLRKR) was used as the immunogen for this CXCL13 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CXCL13 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CXCL13 |
| Short name: |
CXCL13 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-X-C motif) ligand 13 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ANGIE and ANGIE2 and BCA-1 and BCA1 and BLC and BLR1L and SCYB13, CXCL13 and IDBG-25774 and ENSG00000156234 and 10563, CXCL13 and IDBG-643139 and ENSBTAG00000008479 and 511674, CXCR3 chemokine receptor binding, Cxcl13 and IDBG-181227 and ENSMUSG00000023078 and 55985, Extracellular, this GO :0002467 and germinal center formation and biological process this GO :0002518 and lymphocyte chemotaxis across high endothelial venule and biological process this GO :0002544 and chronic inflammatory response and biological process this GO :0002920 and regulation of humoral immune response and biological process this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006955 and immune response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008201 and heparin binding and molecular function this GO :0010820 and positive regulation of T cell chemotaxis and biological process this GO :0017134 and fibroblast growth factor binding and molecular function this GO :0031724 and CXCR5 chemokine receptor binding and molecular function this GO :0031735 and CCR10 chemokine receptor binding and molecular function this GO :0032861 and activation of Rap GTPase activity and biological process this GO :0033625 and positive regulation of integrin activation and biological process this GO :0033634 and positive regulation of cell-cell adhesion mediated by integrin and biological process this GO :0035754 and B cell chemotaxis and biological process this GO :0035768 and endothelial cell chemotaxis to fibroblast growth factor and biological process this GO :0035769 and B cell chemotaxis across high endothelial venule and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0045765 and regulation of angiogenesis and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048018 and receptor a this GO nist activity and molecular function this GO :0048248 and CXCR3 chemokine receptor binding and molecular function this GO :0048535 and lymph node development and biological process this GO :2000545 and negative regulation of endothelial cell chemotaxis to fibroblast growth factor and biological process, this GO :0008009 : chemokine activity, this GO :0008009 : chemokine activity and also this GO :0008201 : heparin binding and also this GO :0017134 : fibroblast growth factor binding and also this GO :0031724 : CXCR5 chemokine receptor binding and also this GO :0031735 : CCR10 chemokine receptor binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0048018 : receptor a this GO nist activity and also this GO :0048248 : CXCR3 chemokine receptor binding, this GO :0008201 : heparin binding, this GO :0017134 : fibroblast growth factor binding, this GO :0031724 : CXCR5 chemokine receptor binding, this GO :0031735 : CCR10 chemokine receptor binding, this GO :0046982 : protein heterodimerization activity, this GO :0048018 : receptor a this GO nist activity, this GO :0048248 : CXCR3 chemokine receptor binding, chemokine (C-X-C motif) ligand 13 |
| Identity: |
10639 |
| Gene: |
CXCL13 |
More about : CXCL13 |
| Long gene name: |
C-X-C motif chemokine ligand 13 |
| Synonyms gene: |
SCYB13 |
| Synonyms gene name: |
member 13 (B-cell chemoattractant) chemokine (C-X-C motif) ligand 13 , small inducible cytokine B subfamily (Cys-X-Cys motif) |
| Synonyms: |
BLC BCA-1 BLR1L ANGIE ANGIE2 |
| Synonyms name: |
B-cell chemoattractant |
| Locus: |
4q21, 1 |
| Discovery year: |
2000-09-05 |
| GenBank acession: |
AJ002211 |
| Entrez gene record: |
10563 |
| Pubmed identfication: |
9463416 9486651 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000130201 |