| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
NDRG1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the NDRG1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This NDRG1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q92597 |
| Purity: |
Antigen affinity |
| Description: |
It has got a deduced 394 amino acid protein with a molecular mass of 43kD, It is a member of the N-myc downregulated gene family which belong to the alpha/beta hydrolase superfamily, NDRG1 is expressed in the cytoplasm and basolateral membranes of gut lumen surface epithelial cells, The NDRG1 gene is mapped to chromosome 8q24, The protein appears to play a vital role in growth arrest and cell differentiation, Protein NDRG1 is a protein that in humans is encoded by the NDRG1 gene |
| Immunogen: |
An amino acid sequence from the middle region of human NDRG1 (HLFGKEEMQSNVEVVHTYRQH) was used as the immunogen for this NDRG1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the NDRG1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
NDRG1 |
| Short name: |
NDRG1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
N-v-myc myelocytomatosis viral oncogene homolog (avian) downstream regulated 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CAP43 and CMT4D and DRG-1 and DRG1 and GC4 and HMSNL and NDR1 and NMSL and PROXY1 and RIT42 and RTP and TARG1 and TDD5, NDRG1 and IDBG-36420 and ENSG00000104419 and 10397, NDRG1 and IDBG-644056 and ENSBTAG00000000711 and 504499, Ndrg1 and IDBG-146853 and ENSMUSG00000005125 and 17988, cadherin binding, nuclei, signal transduction by p53 class mediator and biological process this GO :0032287 and peripheral nervous system myelin maintenance and biological process this GO :0043015 and gamma-tubulin binding and molecular function this GO :0045296 and cadherin binding and molecular function this GO :0045576 and mast cell activation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0055038 and recycling endosome membrane and cellular component this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071456 and cellular response to hypoxia and biological process this GO :0090232 and positive regulation of spindle checkpoint and biological process, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005874 and microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0008017 and microtubule binding and molecular function this GO :0008219 and cell death and biological process this GO :0010038 and response to metal ion and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0017137 and Rab GTPase binding and molecular function this GO :0030330 and DNA damage response, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008017 : microtubule binding and also this GO :0017137 : Rab GTPase binding and also this GO :0043015 : gamma-tubulin binding and also this GO :0045296 : cadherin binding, this GO :0008017 : microtubule binding, this GO :0017137 : Rab GTPase binding, this GO :0043015 : gamma-tubulin binding, this GO :0045296 : cadherin binding, N-myc downstream regulated 1 |
| Identity: |
7679 |
| Gene: |
NDRG1 |
More about : NDRG1 |
| Long gene name: |
N-myc downstream regulated 1 |
| Synonyms gene: |
CAP43 |
| Synonyms: |
DRG1 RTP TDD5 NDR1 |
| Locus: |
8q24, 22 |
| Discovery year: |
1998-12-23 |
| GenBank acession: |
X92845 |
| Entrez gene record: |
10397 |
| Pubmed identfication: |
9251681 8939898 18455888 |
| Havana BLAST/BLAT: |
OTTHUMG00000164441 |
| Locus Specific Databases: |
Inherited Peripheral Neuropathies Mutation Database LRG_258 |