| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Pleiotrophin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Pleiotrophin antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Pleiotrophin antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P21246 |
| Purity: |
Antigen affinity |
| Description: |
A mutant PTN that contained only the first N-terminal 40 amino acids was a dominant negative, PTN is the first member of a family of developmentally regulated cytokines, Pleiotrophin binds to cell-surface nucleolin as a low affinity receptor, Pleiotrophin is expressed in the central and peripheral nervous system and also in several non-neural tissues, The PTN gene is mapped to 7q33-q34, This binding can inhibit HIV infection, gut and bone, kidney, notably lung, Pleiotrophin(PTN) also known as heparin-binding brain mitogen(HBBM) or heparin-binding growth factor 8(HBGF-8) or neurite growth-promoting factor 1(NEGF1) or heparin affinity regulatory peptide(HARP) or heparin binding growth associated molecule(HB-GAM) is a protein that in humans is encoded by the PTN gene |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human Pleiotrophin (QAESKKKKKEGKKQEKMLD) was used as the immunogen for this Pleiotrophin antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Pleiotrophin antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Pleiotrophin |
| Short name: |
Pleiotrophin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Pleiotrophin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9630 |
| Gene: |
PTN |
More about : PTN |
| Long gene name: |
pleiotrophin |
| Synonyms gene: |
NEGF1 |
| Synonyms gene name: |
neurite growth-promoting factor 1 |
| Synonyms: |
HBNF HBGF8 |
| Synonyms name: |
heparin binding growth factor 8 |
| Locus: |
7q33 |
| Discovery year: |
1993-06-22 |
| GenBank acession: |
M57399 |
| Entrez gene record: |
5764 |
| Pubmed identfication: |
1457401 1768439 |
| RefSeq identity: |
NM_002825 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000155709 |