| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
PPAR alpha |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the PPAR alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This PPAR alpha antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P23204 |
| Purity: |
Antigen affinity |
| Description: |
PPAR alpha is a transcription factor and a major regulator of lipid metabolism in the liver, Sher et al, The PPAR cDNA exhibited 85% and 91% DNA and deduced amino acid sequence identity, The gene spans 83, also known as NR1C1 (nuclear receptor subfamily 1, group C, is a nuclear receptor protein that in humans is encoded by the PPARA gene, member 1), respectively, with mouse PPAR, (1993) cloned a cDNA for human peroxisome proliferator-activated receptor from a human liver cDNA library, 1, 7 kb and contains 8 exons and is mapped to chromosome 22q12-q13, Peroxisome proliferator-activated receptor alpha |
| Immunogen: |
Amino acids 393-412 (NIGYIEKLQEGIVHVLKLHL-mouse) were used as the immunogen for this PPAR alpha antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PPAR alpha antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
PPAR alpha |
| Short name: |
PPAR alpha Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PPAR a (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9232 |
| Gene: |
PPARA |
More about : PPARA |
| Long gene name: |
peroxisome proliferator activated receptor alpha |
| Synonyms gene: |
PPAR |
| Synonyms gene name: |
alpha peroxisome proliferator-activated receptor alpha , peroxisome proliferative activated receptor |
| Synonyms: |
hPPAR NR1C1 |
| Locus: |
22q13, 31 |
| Discovery year: |
1993-11-01 |
| GenBank acession: |
L02932 |
| Entrez gene record: |
5465 |
| Pubmed identfication: |
7684926 10591208 |
| RefSeq identity: |
NM_001001928 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000150443 |