| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Synaptopodin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Synaptopodin antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Synaptopodin antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q8N3V7 |
| Purity: |
Antigen affinity |
| Description: |
In summary, Mice that lack the gene for synaptopodin do not form a spine apparatus, The International Radiation Hybrid Mapping Consortium mapped the SYNPO gene to chromosome 5, The SA consists of a series of stacked discs that are though to be connected to each other and to the dendritic system of ER-tubules, The SA is believed to play a critical role in learning and memory, The actin binding protein synaptopodin(which has originally been described in podocytes of the kidney) is an essential component of the SA, a process known as metaplasticity, an important function of the spine apparatus is the regulation of plasticity at individual synapses, The spine apparatus(SA) is a specialized form of endoplasmic reticulum(ER) that is found in a subpopulation of dendritic spines in central neurons |
| Immunogen: |
mouse and rat), An amino acid sequence from the middle region of human Synaptopodin (TSQMERSPMLERRHF) was used as the immunogen for this Synaptopodin antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Synaptopodin antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Synaptopodin |
| Short name: |
Synaptopodin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Synaptopodin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
23532 |
| Gene: |
SYNPO2L |
More about : SYNPO2L |
| Long gene name: |
synaptopodin 2 like |
| Synonyms gene name: |
synaptopodin 2-like |
| Synonyms: |
FLJ12921 |
| Locus: |
10q22, 2 |
| Discovery year: |
2003-11-21 |
| GenBank acession: |
AK022983 |
| Entrez gene record: |
79933 |
| RefSeq identity: |
NM_024875 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000018471 |