| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
IL1 alpha |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the IL1 alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This IL1 alpha antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P01582 |
| Purity: |
Antigen affinity |
| Description: |
Further studies suggested that Il1b lies 5-prime to Il1a, Interleukin-1 alpha possesses a wide spectrum of metabolic, It binds to the interleukin-1 receptor, Silver et al, The protein encoded by this gene is a cytokine of the interleukin-1 family, and plays one of the central roles in the regulation of the immune responses, and that they are separated by about 50 kb, haematopoietic activities, physiological, that the 2 genes are oriented in the same direction, (1990) showed that the mouse Il1a and Il1b genes are contained in a genomic fragment of about 70 kb, Interleukin-1 alpha(IL-1alpha) is a protein that in humans is encoded by the IL1A gene |
| Immunogen: |
An amino acid sequence from the C-terminus of mouse IL1 alpha (HLARGLPSMTDFQIS) was used as the immunogen for this IL1 alpha antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the IL1 alpha antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
IL1 alpha |
| Short name: |
IL1 alpha Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
IL1 a (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
5991 |
| Gene: |
IL1A |
More about : IL1A |
| Long gene name: |
interleukin 1 alpha |
| Synonyms gene: |
IL1 |
| Synonyms: |
IL1F1 IL-1A IL1-ALPHA |
| Synonyms name: |
preinterleukin 1 alpha hematopoietin-1 pro-interleukin-1-alpha |
| Locus: |
2q14, 1 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M28983 |
| Entrez gene record: |
3552 |
| Pubmed identfication: |
8188271 2989698 |
| RefSeq identity: |
NM_000575 |
| Classification: |
Endogenous ligands Interleukins |
| Havana BLAST/BLAT: |
OTTHUMG00000131315 |