| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FGF8 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the FGF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This FGF8 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P55075 |
| Purity: |
Antigen affinity |
| Description: |
A survey of other normal tissues showed that FGF8 is expressed in the proliferative cells of the skin and epithelial cells in colon, FGF8 is expressed in increased levels in breast cancer and in lactating human breast, FGF8 stimulated growth of human prostate carcinoma cells and mouse fibroblasts and mammary carcinoma cells in a dose-dependent manner, It also may play an important role in growth and patterning of limbs, Overexpression of this gene has been shown to increase tumor growth and angiogensis, The adult expression of FGF8 is restricted to gonads, The protein encoded by this gene are secreted proteins that interact with FGF tyrosine kinase receptors to mediate growth and development, The temporal and spatial patterns of this gene expression suggest that FGF8 is involved in gastrulation, This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells, also known as FGF8 or AIGF, and central nervous system, and organogenesis of the limb and face as an embryonic epithelial factor, and uterus, face, fallopian tube, including testes and ovaries, is a human gene which maps to 10q24, it was also detected in human milk, ovary, regionalization of the brain, Fibroblast growth factor 8(androgen-induced) |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human FGF8 (FMKRLPRGHHTTEQSLRFEFLNY) was used as the immunogen for this FGF8 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FGF8 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FGF8 |
| Short name: |
FGF8 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FGF8 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3686 |
| Gene: |
FGF8 |
More about : FGF8 |
| Long gene name: |
fibroblast growth factor 8 |
| Synonyms gene name: |
fibroblast growth factor 8 (androgen-induced) |
| Synonyms: |
AIGF |
| Synonyms name: |
androgen-induced growth factor |
| Locus: |
10q24, 32 |
| Discovery year: |
1995-08-15 |
| GenBank acession: |
D38752 |
| Entrez gene record: |
2253 |
| Pubmed identfication: |
8595889 |
| RefSeq identity: |
NM_006119 NM_033165 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000018940 |