| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
AChR (nicotinic) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the AChR antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This AChR antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P02708 |
| Purity: |
Antigen affinity |
| Description: |
The protein-coding sequence of the human alpha subunit gene is divided into 9 exons that correspond to different structural and functional domains of the precursor molecule, This gene encodes the alpha subunit of the muscle acetylcholine receptor, also called CHRNA, is mapped on 2q24-q32, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis, AChR alpha |
| Immunogen: |
Amino acids 22-36 (EHETRLVAKLFKDYS) from the alpha subunit were used as the immunogen for this nicotinic AChR antibody (100% homologous in human and rat) |
| Storage: |
After reconstitution, Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, Store the lyophilized AChR antibody at 4oC |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
AChR (nicotinic) |
| Short name: |
AChR Antibody (nicotinic) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
AChR (Antibody to) (nicotinic) |
| Alternative technique: |
antibodies |