| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
OPCML |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the OPCML antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This OPCML antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q14982 |
| Purity: |
Antigen affinity |
| Description: |
And due to the lack of transmembrane domains necessary for signal transduction, OPCML is a member of the IgLON family of immunoglobulin(Ig) domain-containing glycosylphosphatidylinositol(GPI)-anchored cell adhesion molecules, The OPCML gene comprises 7 exons, and is transcribed from telomere to centromere , as an excellent candidate for the 11q25 ovarian cancer TSG in EOC, it is improbable that OBCAM acts independently as an opioid receptor, it plays an important accessory role in opioid receptor function, more likely, spans approximately 600 kb, (also called opioid-binding cell adhesion molecule(OBCAM), Opioid-binding protein/cell adhesion molecule-like(OPCML) |
| Immunogen: |
mouse and rat), An amino acid sequence from the C-terminus of human OPCML (YTCVATNKLGNTNASITLY) was used as the immunogen for this OPCML antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the OPCML antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
OPCML |
| Short name: |
OPCML Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
opioid binding protein/cellular adhesion molecule-like (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
IGLON1 and OBCAM and OPCM, OPCML and IDBG-642835 and ENSBTAG00000020769 and, OPCML and IDBG-76356 and ENSG00000183715 and 4978, Opcml and IDBG-146160 and ENSMUSG00000062257 and 330908, Plasma membranes, protein binding, this GO :0004985 and opioid receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0008038 and neuron recognition and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0038003 and opioid receptor signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004985 : opioid receptor activity, this GO :0004985 : opioid receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, opioid binding protein/cell adhesion molecule-like |
| Identity: |
8143 |
| Gene: |
OPCML |
More about : OPCML |
| Long gene name: |
opioid binding protein/cell adhesion molecule like |
| Synonyms: |
OPCM OBCAM IGLON1 |
| Synonyms name: |
IgLON family member 1 |
| Locus: |
11q25 |
| Discovery year: |
1993-12-13 |
| GenBank acession: |
BX537377 |
| Entrez gene record: |
4978 |
| Pubmed identfication: |
8244387 |
| RefSeq identity: |
NM_001012393 |
| Classification: |
I-set domain containing IgLON cell adhesion molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000163658 |