| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
OPCML |
| Specificity: |
This antibody reacts specifically with OPCML |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human OPCML |
| Gene ID: |
4978 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Since the encoded protein is highly conserved in species during evolution, The encoded protein is localized in the plasma membrane and may have an accessory role in opioid receptor function, The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, This gene has an ortholog in rat and bovine, Two transcript variants encoding different isoforms have been found for this gene, [provided by RefSeq], exhibits selectivity for mu ligands and acts as a GPI-anchored protein, it may have a fundamental role in mammalian systems, This gene encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
OPCM OBCAM IGLON1 |
| Also known as: |
OPCML Polyclonal Antibody |
| Other name: |
Anti-OPCML Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
OPCML |
| Short name: |
Anti-OPCML (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-opioid binding protein/cellular adhesion molecule-like (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
IGLON1 and OBCAM and OPCM, OPCML and IDBG-642835 and ENSBTAG00000020769 and, OPCML and IDBG-76356 and ENSG00000183715 and 4978, Opcml and IDBG-146160 and ENSMUSG00000062257 and 330908, Plasma membranes, protein binding, this GO :0004985 and opioid receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0008038 and neuron recognition and biological process this GO :0031225 and anchored component of membrane and cellular component this GO :0038003 and opioid receptor signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004985 : opioid receptor activity, this GO :0004985 : opioid receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, opioid binding protein/cell adhesion molecule-like |
| Identity: |
8143 |
| Gene: |
OPCML |
More about : OPCML |
| Long gene name: |
opioid binding protein/cell adhesion molecule like |
| Synonyms name: |
IgLON family member 1 |
| Locus: |
11q25 |
| Discovery year: |
1993-12-13 |
| GenBank acession: |
BX537377 |
| Entrez gene record: |
4978 |
| Pubmed identfication: |
8244387 |
| RefSeq identity: |
NM_001012393 |
| Classification: |
I-set domain containing IgLON cell adhesion molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000163658 |