| Catalog number: | R30238 |
|---|---|
| Price: | 368 € |
| Supplier: | Bioss Primary Conjugated Antibodies |
| Product name: | NMDAR2A Antibody |
| Quantity: | 0.1ml |
| Other quantities: | 0.1ml 263€ |
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| Category: | Antibody |
|---|---|
| Concentration: | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: | Antigen affinity purified |
| Conjugation: | Unconjugated |
| Clone: | Polyclonal antibody |
| Recognised antigen: | NMDAR2A |
| Host animal: | Rabbit (Oryctolagus cuniculus) |
| Clonality: | Polyclonal (rabbit origin) |
| Species reactivity: | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: | IHC-P, WB |
| Recommended dilutions: | 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: | Titration of the NMDAR2A antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: | This NMDAR2A antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: | Q12879 |
| Purity: | Antigen affinity |
| Description: | Alternative splicing results in multiple transcript variants, Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation, NMDA receptors are both ligand-gated and voltage-dependent, The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit, These receptors are permeable to calcium ions, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning, and activation results in a calcium influx into post-synaptic cells, and are involved in long-term potentiation, subunit epsilon-1(NMDAR2A or NR2A) is a member of the glutamate-gated ion channel protein family, which results in the activation of several signaling cascades, N-methyl-D-aspartate receptor channel |
| Immunogen: | An amino acid sequence from the C-terminus of human NMDAR2A (DHTSDNPFLHSHRDDQR) was used as the immunogen for this NMDAR2A antibody |
| Storage: | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the NMDAR2A antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: | NMDAR2A |
| Short name: | NMDAR2A Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Alternative name: | NMDAR2A (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 4585 |
| Gene: | GRIN2A | More about : GRIN2A |
| Long gene name: | glutamate ionotropic receptor NMDA type subunit 2A |
| Synonyms gene: | NMDAR2A |
| Synonyms gene name: | N-methyl D-aspartate 2A , glutamate receptor, ionotropic |
| Synonyms: | GluN2A |
| Locus: | 16p13, 2 |
| Discovery year: | 1992-09-18 |
| Pubmed identfication: | 9480759 |
| Classification: | Glutamate ionotropic receptor NMDA type subunits |
| Havana BLAST/BLAT: | OTTHUMG00000129721 |
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