| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
INSL3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the INSL3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This INSL3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P51460 |
| Purity: |
Antigen affinity |
| Description: |
INSL3 induces gubernaculum development in an androgen-independent way, INSL3 is a ligand for LGR8 and INSL3-LGR8 mutations are believed to be associated with human cryptorchidism, It is synthesized as a 131-amino acid preproprotein, Moreover, The human INSL3 gene is assigned to bands p13, a member of the insulin-like hormone superfamily, is specifically expressed in Leydig cells of the fetal and postnatal testis and in theca cells of the postnatal ovary, which contains a 24-amino acid signal peptide, while androgen-mediated regression of the CSL occurs independently from Insl3, 2-p12 of the short arm of chromosome 19 with the similar organization to that of insulin and relaxin, Insulin-like 3(INSL3) |
| Immunogen: |
An amino acid sequence from the C-terminus of human INSL3 (CCLSGCTQQDLLTLCPY) was used as the immunogen for this INSL3 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the INSL3 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
INSL3 |
| Short name: |
INSL3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
INSL3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6086 |
| Gene: |
INSL3 |
More about : INSL3 |
| Long gene name: |
insulin like 3 |
| Synonyms gene: |
RLNL |
| Synonyms gene name: |
relaxin-like factor insulin-like 3 (Leydig cell) |
| Synonyms: |
RLF MGC119818 MGC119819 |
| Synonyms name: |
prepro-INSL3 |
| Locus: |
19p13, 11 |
| Discovery year: |
1993-11-02 |
| Entrez gene record: |
3640 |
| Pubmed identfication: |
8020942 |
| RefSeq identity: |
NM_005543 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000183481 |