| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
EAAT2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the EAAT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This EAAT2 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
6506 |
| Purity: |
Antigen affinity |
| Description: |
Alternatively spliced transcript variants of this gene have been identified, Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors, Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis, The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system, This gene encodes a member of a family of solute transporter proteins, SLC1A2 is also known as EAAT2 or GLT-1 |
| Immunogen: |
Human partial recombinant protein (AA 461-574) was used as the immunogen for this EAAT2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the EAAT2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
EAAT2 |
| Short name: |
EAAT2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
EAAT2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10940 |
| Gene: |
SLC1A2 |
More about : SLC1A2 |
| Long gene name: |
solute carrier family 1 member 2 |
| Synonyms gene name: |
member 2 , solute carrier family 1 (glial high affinity glutamate transporter) |
| Synonyms: |
GLT-1 EAAT2 |
| Locus: |
11p13 |
| Discovery year: |
1994-02-15 |
| GenBank acession: |
AB209444 |
| Entrez gene record: |
6506 |
| Pubmed identfication: |
1448170 |
| RefSeq identity: |
NM_004171 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000044391 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |