| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
MBD2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the MBD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This MBD2 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
8932 |
| Purity: |
Antigen affinity |
| Description: |
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development, Each of these proteins, Human proteins MECP2, It is also reported that this protein functions as a demethylase to activate transcription, It is mapped to 18q21, MBD1, MBD2, MBD3, The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG-binding domain (MBD), as DNA methylation causes gene silencing, is capable of binding specifically to methylated DNA, with the exception of MBD3, 2, Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene |
| Immunogen: |
Human partial recombinant protein (AA 159-411) was used as the immunogen for this MBD2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the MBD2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
MBD2 |
| Short name: |
MBD2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MBD2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6917 |
| Gene: |
MBD2 |
More about : MBD2 |
| Long gene name: |
methyl-CpG binding domain protein 2 |
| Locus: |
18q21, 2 |
| Discovery year: |
1999-01-11 |
| GenBank acession: |
AF072242 |
| Entrez gene record: |
8932 |
| Pubmed identfication: |
9774669 10441743 |
| RefSeq identity: |
NM_003927 |
| Classification: |
NuRD complex Methyl-CpG binding domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132705 |