| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ANG2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P |
| Recommended dilutions: |
5-1ug/ml, IHC (Paraffin): 0 |
| Notes: |
Titration of the ANG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This ANG2 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
285 |
| Purity: |
Antigen affinity |
| Description: |
ANGPT2 is a naturally occurring antagonist of ANGPT1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation during vasculogenesis, ANGPT2 was also significantly increased in neonates with respiratory distress syndrome who developed bronchopulmonary edema, ANGPT2 was significantly increased in plasma and alveolar edema fluid in adults with acute lung injury compared to controls or patients with hydrostatic pulmonary edema, It is also a mediator of epithelial necrosis with an important role in hyperoxic acute lung injury and pulmonary edema, It is mapped to 8p23, The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis, also known as ANG2, is a protein that in humans is encoded by the ANGPT2 gene, tracheal, 1, Angiopoietin 2 |
| Immunogen: |
Human partial recombinant protein (AA 19-348) was used as the immunogen for this ANG2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ANG2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ANG2 |
| Short name: |
ANG2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ANG2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
485 |
| Gene: |
ANGPT2 |
More about : ANGPT2 |
| Long gene name: |
angiopoietin 2 |
| Synonyms: |
Ang2 |
| Locus: |
8p23, 1 |
| Discovery year: |
1997-07-22 |
| GenBank acession: |
AF004327 |
| Entrez gene record: |
285 |
| Pubmed identfication: |
9545648 |
| RefSeq identity: |
NM_001147 |
| Classification: |
Fibrinogen C domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000090365 |