| Gene info: |
Artificial stem cells, KLF4 interacts directly with POU5F1 and Sox2 in iPS and ES cells and activates the target gene NANOG, More recently, POU5F1 and c-Myc, Sox2, Sox2, The role of KLF4 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases, and Lin28 along with c-Myc in mouse fibroblasts, can be created by expressing KLF4 and the transcription factors POU5F1, eliminating the need for virus introduction, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing KLF4, termed induced pluripotent stem (iPS) cells, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine, KLF4 Monoclonal Antibody: KLF4 is a transcription factor that functions as both a transcriptional activator and repressor to regulate proliferation and differentiation of multiple cell types |
| Gene names: |
GKLF, KLF4 Antibody [4E5C3] : EZF |
| Antibodie's label: |
unlabelled serum |
| Purity: |
KLF4 Monoclonal Antibody is affinity chromatography purified via peptide column |
| Ab raised in: |
Mouse |
| Type: |
Monoclonal |
| Monoclonal: |
4E5C3 |
| Immunoglobulin: |
IgG1 |
| Spicific to: |
KLF4 antibody will not cross-react with other Kruppel-like family members, this antibody will detect all three, At least three isoforms of KLF4 are known to exist |
| Antigen: |
KLF4 antibody was made against a 20 amino acid synthetic peptide near the carboxy terminus of human KLF4 |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
KLF4 antibody can be used for detection of KLF4 by Western blot at 1 ug/mL |
| Suspention, pH, azide: |
02% sodium azide, KLF4 Monoclonal Antibody is supplied in PBS containing 0 |
| Keep at: |
stable for one year, KLF4 monoclonal antibody can be stored at -20 grades C |
| Works with: |
Mouse, Rat, Human |
| Omim nr: |
21410813 |
| Ncbi nr: |
AAH30811 |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
9314 |
| GENE symbol: |
KLF4 |
| Antigene name: |
Kruppel-like factor 4 (gut) |
| Source: |
homo sapiens |
| Protein nr: |
O43474 |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
KLF4 [4E5C3] |
| Short name: |
anti-KLF4 Antibody [4E5C3] |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-KLF4 (Antibody to) [4E5C3] |
| Alternative technique: |
antibodies |
| Identity: |
6348 |
| Gene: |
KLF4 |
More about : KLF4 |
| Long gene name: |
Kruppel like factor 4 |
| Synonyms gene name: |
Kruppel-like factor 4 (gut) |
| Synonyms: |
EZF GKLF |
| Synonyms name: |
gut Kruppel-like factor |
| Locus: |
9q31, 2 |
| Discovery year: |
1999-12-14 |
| GenBank acession: |
AF022184 |
| Entrez gene record: |
9314 |
| Pubmed identfication: |
9422764 16372018 |
| RefSeq identity: |
NM_004235 |
| Classification: |
Kruppel like factors Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000020449 |