| Gene info: |
It has been shown that the V-like domains are critical for binding with HIV envelope gp120, On T-lymphocytes, The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions, binding directly to the envelope glycoprotein gp120 on HIV, it defines the helper/inducer subset, with the co-receptors being CCR5 or CXCR4, CD4 Monoclonal Antibody: CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response |
| Gene names: |
CD4 Antibody [9H5A8] : CD4mut |
| Antibodie's label: |
unlabelled serum |
| Purity: |
CD4 Monoclonal Antibody is immunoaffinity chromotography purified IgG |
| Ab raised in: |
Mouse |
| Type: |
Monoclonal |
| Monoclonal: |
9H5A8 |
| Immunoglobulin: |
IgG1 |
| Antigen: |
Mouse monoclonal CD4 antibody was made against a 193 amino acid recombinant protein from near the amino terminus of human CD4 |
| Immuno application: |
Western Blot, ELISA |
| Antibody advice: |
5 - 1 ug/mL, CD4 antibody can be used for detection of CD4 by Western blot at 0 |
| Suspention, pH, azide: |
02% sodium azide, CD4 Monoclonal Antibody is supplied in PBS containing 0 |
| Keep at: |
stable for one year, CD4 monoclonal antibody can be stored at -20 grades C |
| Works with: |
Mouse, Rat, Human |
| Omim nr: |
10835167 |
| Ncbi nr: |
NP_000607 |
| Vial with antibody: |
in solution |
| Quantity per ml: |
1 mg/mL |
| NCBI GENE nr: |
920 |
| GENE symbol: |
CD4 |
| Antigene name: |
CD4 molecule |
| Source: |
homo sapiens |
| Protein nr: |
P01730 |
| Description: |
CD4+ T helper cell marker or cluster differentiator of white blood cells in FACS or flow cytometry, Freeze thaw will destroy a percentage in every cycle and should be avoided, GENTAUR makes custom magnetic bead couplings on 50 and 250 nm beads for certain clones, Used offer coupled to magnetic beads, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by proscience they should be stored frozen at - 24° |
| Gene target: |
CD4 [9H5A8] |
| Short name: |
anti-CD4 Antibody [9H5A8] |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, Antibody |
| Alternative name: |
antibody to-CD4 molecule (Antibody to) [9H5A8] |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD4 and IDBG-15034 and ENSG00000010610 and 920, CD4 and IDBG-640247 and ENSBTAG00000003255 and 407098, CD4mut, Cd4 and IDBG-188351 and ENSMUSG00000023274 and 12504, Cell surfaces, protein homodimerization activity, this GO :0001816 and cytokine production and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0004872 and receptor activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005201 and extracellular matrix structural constituent and molecular function this GO :0005515 and protein binding and molecular function this GO :0005769 and early endosome and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006948 and induction by virus of host cell-cell fusion and biological process this GO :0006955 and immune response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007167 and enzyme linked receptor protein signaling pathway and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030217 and T cell differentiation and biological process this GO :0030260 and entry into host cell and biological process this GO :0031295 and T cell costimulation and biological process this GO :0032507 and maintenance of protein location in cell and biological process this GO :0042101 and T cell receptor complex and cellular component this GO :0042110 and T cell activation and biological process this GO :0042289 and MHC class II protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0045058 and T cell selection and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045234 and protein palmitoleylation and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050829 and defense response to Gram-negative bacterium and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050863 and regulation of T cell activation and biological process this GO :0050870 and positive regulation of T cell activation and biological process, this GO :0001948 : glycoprotein binding, this GO :0001948 : glycoprotein binding and also this GO :0004872 : receptor activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005201 : extracellular matrix structural constituent and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0015026 : coreceptor activity and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0042289 : MHC class II protein binding and also this GO :0042803 : protein homodimerization activity, this GO :0004872 : receptor activity, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005201 : extracellular matrix structural constituent, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0015026 : coreceptor activity, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0042289 : MHC class II protein binding, this GO :0042803 : protein homodimerization activity, CD4 molecule |
| Identity: |
1678 |
| Gene: |
CD4 |
More about : CD4 |
| Long gene name: |
CD4 molecule |
| Synonyms gene name: |
CD4 antigen (p55) T-cell surface glycoprotein CD4 |
| Locus: |
12p13, 31 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M35160 |
| Entrez gene record: |
920 |
| RefSeq identity: |
NM_000616 |
| Classification: |
C2-set domain containing CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000168514 |