| Category: |
Antibody |
| Concentration: |
05% sodium azide, 1 mg/ml BSA (US sourced) and 0, 5 mg/ml in 1X PBS with 0 |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
LSD1 / KDM1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-2ug/ml, Western blot: 0 |
| Notes: |
LSD1 / KDM1 antibody titration may be required for optimal results, Provided assay concentrations are suggestions only |
| Added buffer: |
pH 7, 1X Phosphate Buffered Saline (PBS), 4 |
| Intented use: |
This LSD1 KDM1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
23028 |
| Purity: |
Purified by protein A Affinity Chromatography |
| Description: |
2012), It also plays a role in tumor development where overexpression of LSD1 correlates with a poor prognosis, It is upregulated in cancers of the bladder, It negatively regulates pro-inflammatory cytokine expression by interacting with the genes promoter region, also called KDM1 (lysine (K)-specific demethylase 1A), and GI tract as well as neuroblastoma and cells of mesenchymal origin such as chondrosarcoma, breast, colon, is the first histone demethylase to be identified and regulates transcription via demethylation of lysines 4 and 9 of Histone H3, lung, osteosarcoma, rhabdomyosarcoma and Ewing's sarcoma (Bennani-Baiti et al, LSD1 (Lysine-specific demethylase 1) |
| Immunogen: |
A recombinant protein fragment from the N-terminal region of human LSD1 / KDM1 was used as the immunogen for this antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the LSD1 / KDM1 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene: |
KDM1A |
More about : KDM1A |
| Gene target: |
LSD1 / KDM1 |
| Short name: |
LSD1 / KDM1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
LSD1 / KDM1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29079 |
| Long gene name: |
lysine demethylase 1A |
| Synonyms gene: |
AOF2 KDM1 |
| Synonyms gene name: |
amine oxidase (flavin containing) domain 2 lysine (K)-specific demethylase 1 |
| Synonyms: |
KIAA0601 BHC110 LSD1 |
| Locus: |
1p36, 12 |
| Discovery year: |
2004-02-26 |
| GenBank acession: |
AL031428 |
| Entrez gene record: |
23028 |
| Pubmed identfication: |
9628581 12493763 |
| RefSeq identity: |
NM_015013 |
| Classification: |
Lysine demethylases |
| Havana BLAST/BLAT: |
OTTHUMG00000003220 |