| Category: |
Antibody |
| Concentration: |
05% sodium azide, 1 mg/ml BSA (US sourced) and 0, 5 mg/ml in 1X PBS with 0 |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CLEC4E |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 2-5ug/ml |
| Notes: |
CLEC4E antibody titration may be required for optimal results, Provided assay concentrations are suggestions only |
| Added buffer: |
pH 7, 1X Phosphate Buffered Saline (PBS), 4 |
| Intented use: |
This CLEC4E antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
26253 |
| Purity: |
Purified by protein A Affinity Chromatography |
| Description: |
130kDa), CLEC4E, CLEC4E senses this and interacts with the ITAM-containing adaptor protein FcR&, Dead cells release SAP130 (Sin3A-Associated Protein, It is a receptor for both non-self (fungi and mycobacteria), MIP-2 and IL-6, a small nuclear ribonucleoprotein component, activates the production of inflammatory cytokines such as TNFa, also called Mincle (Macrophage-inducible C-type lectin), and self (damaged cells) ligands, and via Syk and CARD9 signaling, is found on the surface of activated macrophages and phagocytes, #947, CLEC4 is a member of the C-type lectin family of proteins that plays a role in inflammatory and immune response |
| Immunogen: |
A recombinant protein fragment from the C-terminal portion of human CLEC4E was used as the immunogen for this antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the CLEC4E antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CLEC4E |
| Short name: |
CLEC4E Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CLEC4E (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
14555 |
| Gene: |
CLEC4E |
More about : CLEC4E |
| Long gene name: |
C-type lectin domain family 4 member E |
| Synonyms gene: |
CLECSF9 |
| Synonyms gene name: |
C-type (calcium dependent, carbohydrate-recognition domain) lectin, member E , superfamily member 9 C-type lectin domain family 4 |
| Synonyms: |
mincle |
| Synonyms name: |
Macrophage-inducible C-type lectin |
| Locus: |
12p13, 31 |
| Discovery year: |
2001-02-01 |
| GenBank acession: |
AB024718 |
| Entrez gene record: |
26253 |
| Pubmed identfication: |
10528209 |
| RefSeq identity: |
NM_014358 |
| Classification: |
C-type lectin domain family |
| Havana BLAST/BLAT: |
OTTHUMG00000168675 |