| Category: |
Antibody |
| Concentration: |
05% sodium azide, 1 mg/ml BSA (US sourced) and 0, 5 mg/ml in 1X PBS with 0 |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Als2Cr2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 5-10ug/ml |
| Notes: |
Als2Cr2 antibody titration may be required for optimal results, This antibody will detect the 418 (ILPIP alpha) and 280 (ILPIP beta) amino acid isoforms, Provided assay concentrations are suggestions only |
| Added buffer: |
pH 7, 1X Phosphate Buffered Saline (PBS), 4 |
| Intented use: |
This Als2Cr2 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
55437 |
| Purity: |
Purified by protein A Affinity Chromatography |
| Description: |
Alone, It is a mediator of the XIAP/TAK1 activation of the JNK1 pathway, also called STE20-related kinase adapter protein beta (STRAD beta) and ILPIP, an apoptosis inhibition mechanism independent of XIAP inhibition of caspases, but its interaction with XIAP/TAK1 induces a much stronger activation of JNK1, discovered as an XIAP interacting protein, is a serine/threonine protein kinase encoded by the STRADB gene, it only moderately activates JNKs, protecting against Caspase 1- or Fas-induced apoptosis, Als2Cr2 |
| Immunogen: |
A recombinant protein fragment from the interior region of human Als2Cr2 was used as the immunogen for this antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the Als2Cr2 antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Als2Cr2 |
| Short name: |
Als2Cr2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Als2Cr2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
13205 |
| Gene: |
STRADB |
More about : STRADB |
| Long gene name: |
STE20-related kinase adaptor beta |
| Synonyms gene: |
ALS2CR2 |
| Synonyms gene name: |
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2 |
| Synonyms: |
CALS-21 PAPK ILPIPA ILPIP |
| Locus: |
2q33, 1 |
| Discovery year: |
2001-02-13 |
| GenBank acession: |
AB038950 |
| Entrez gene record: |
55437 |
| Pubmed identfication: |
11161814 14511394 |
| RefSeq identity: |
NM_018571 |
| Havana BLAST/BLAT: |
OTTHUMG00000132831 |