| Category: |
Antibody |
| Concentration: |
05% sodium azide, 5 mg/ml in 1X PBS with 0 |
| Form: |
Purified |
| Conjugation: |
APC Conjugate |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Rabbit IgG Isotype Control APC Conjugate |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
isotype control Igs |
| Tested applications: |
IF, IHC, FACS |
| Recommended dilutions: |
FACS: assay dependent, IF: assay dependent, IHC: assay dependent |
| Notes: |
Generally to be used at the same concentration as the sample being controlled for |
| Added buffer: |
pH 7, 1X Phosphate Buffered Saline (PBS), 4 |
| Intented use: |
This Rabbit IgG isotype control antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
NA |
| Purity: |
Purified by protein A Affinity Chromatography |
| Description: |
They are not specific to any target in a cell, yet retain all non-specific characteristics of the antibodies they control, Isotype control antibodies are negative controls used to measure non-specific binding or background levels of a primary antibody in different cell types |
| Immunogen: |
This is purified native rabbit sera and as such there was no immunogen |
| Storage: |
Do not freeze, protect from light, Store the Rabbit IgG isotype control antibody at 4oC |
| Properties: |
Also polyclonal antibodies are Isotype purified amd conjugated or if they are used as control non conjugated, Immunoglobulin Isotype specific antibodies and controls are specific to the immunoglobulin heavy chains , Mouse monoclonal antibodies from this clone have all the same affinity to the antigen, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°, and , immunoglobulin light chains |
| About: |
2 light chains, Anti-human, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, NJS poly adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies, Polyclonals can be used for Western blot, Rabbit antibodies are very stable and can be stored for several days at room temperature, Rabbits are used for polyclonal antibody production by NJS poly, The IgG antibody has 2 , The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, anti mouse antibodies to highly immunogenic selected peptide sequences are", goat polyclonal antibodies , immunohistochemistry on frozen slices or parrafin fixed tissues, monoclonal like", mouse monoclonal H&, since the epitope to which they are directed is less than 35 amino acids long, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Group: |
Polyclonals and antibodies, isotypes |
| Latin name: |
Oryctolagus cuniculus |
| Gene target: |
APC Conjugate |
| Short name: |
Rabbit IgG Isotype Control Polyclonal Antibody APC Conjugate |
| Technique: |
IgGs, Isotypes and controls, Pabs are a collection of immunoglobulin , Polyclonal antibodies , antibodies against human proteins, antibodies for, controls, each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Host: |
Rabbits, Rabbit |
| Isotype: |
IgG |
| Label: |
APC |
| Alternative name: |
production species: rabbit Immunoglobulin G isoform reference polyclonal (Antibody to) adenomatous polyposis coli Conjugate |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
APC and IDBG-37007 and ENSG00000134982 and 324, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT, BTPS2 and DP2 and DP2, microtubule plus-end binding, nuclei, this GO :0000281 and mitotic cytokinesis and biological process this GO :0000776 and kinetochore and cellular component this GO :0001822 and kidney development and biological process this GO :0001942 and hair follicle development and biological process this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005881 and cytoplasmic microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007026 and negative regulation of microtubule depolymerization and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007091 and metaphase/anaphase transition of mitotic cell cycle and biological process this GO :0007094 and mitotic spindle assembly checkpoint and biological process this GO :0007155 and cell adhesion and biological process this GO :0007389 and pattern specification process and biological process this GO :0007409 and axonogenesis and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008017 and microtubule binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009798 and axis specification and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0009953 and dorsal/ventral pattern formation and biological process this GO :0009954 and proximal/distal pattern formation and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016328 and lateral plasma membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0019887 and protein kinase regulator activity and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030027 and lamellipodium and cellular component this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030424 and axon and cellular component this GO :0030426 and growth cone and cellular component this GO :0030856 and regulation of epithelial cell differentiation and biological process this GO :0030858 and positive regulation of epithelial cell differentiation and biological process this GO :0030877 and beta-catenin destruction complex and cellular component this GO :0031116 and positive regulation of microtubule polymerization and biological process this GO :0031122 and cytoplasmic microtubule organization and biological process this GO :0031253 and cell projection membrane and cellular component this GO :0031274 and positive regulation of pseudopodium assembly and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032886 and regulation of microtubule-based process and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0035371 and microtubule plus-end and cellular component this GO :0042483 and negative regulation of odontogenesis and biological process this GO :0042995 and cell projection and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0043588 and skin development and biological process this GO :0044295 and axonal growth cone and cellular component this GO :0044336 and canonical Wnt signaling pathway involved in negative regulation of apoptotic process and biological process this GO :0044337 and canonical Wnt signaling pathway involved in positive regulation of apoptotic process and biological process this GO :0045295 and gamma-catenin binding and molecular function this GO :0045595 and regulation of cell differentiation and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045667 and regulation of osteoblast differentiation and biological process this GO :0045670 and regulation of osteoclast differentiation and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0046716 and muscle cell cellular homeostasis and biological process this GO :0048538 and thymus development and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0051010 and microtubule plus-end binding and molecular function this GO :0051171 and regulation of nitrogen compound metabolic process and biological process this GO :0051276 and chromosome organization and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0051988 and regulation of attachment of spindle microtubules to kinetochore and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060770 and negative regulation of epithelial cell proliferation involved in prostate gland development and biological process this GO :0070830 and tight junction assembly and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process, this GO :0005488 : binding, this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0008013 : beta-catenin binding and also this GO :0008017 : microtubule binding and also this GO :0019887 : protein kinase regulator activity and also this GO :0019901 : protein kinase binding and also this GO :0045295 : gamma-catenin binding and also this GO :0051010 : microtubule plus-end binding, this GO :0005515 : protein binding, this GO :0008013 : beta-catenin binding, this GO :0008017 : microtubule binding, this GO :0019887 : protein kinase regulator activity, this GO :0019901 : protein kinase binding, this GO :0045295 : gamma-catenin binding, this GO :0051010 : microtubule plus-end binding, 25770 and IDBG-644937 and ENSBTAG00000018852 and 533233, 5 and DP3 and GS and PPP1R46, adenomatous polyposis coli |
| Identity: |
583 |
| Gene: |
APC |
More about : APC |
| Long gene name: |
APC, WNT signaling pathway regulator |
| Synonyms gene name: |
adenomatosis polyposis coli adenomatous polyposis coli |
| Synonyms: |
DP2 DP3 DP2, 5 PPP1R46 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 46 |
| Locus: |
5q22, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M74088 |
| Entrez gene record: |
324 |
| Pubmed identfication: |
1651563 |
| RefSeq identity: |
NM_000038 |
| Classification: |
Protein phosphatase 1 regulatory subunits Armadillo repeat containing |
| Havana BLAST/BLAT: |
OTTHUMG00000128806 |
| Locus Specific Databases: |
Adenomatous polyposis coli mutation database UMD Locus Specific Databases Colon cancer gene variant databases APC database at LOVD-China LOVD - Leiden Open Variation Database LRG_130 |