| Alternative name 1: |
Clone: 64A6, IH/No WB, Mab anti-Human, Mort-1, frozen/paraffin, Fas-Associated Death Domain Protein (FADD) |
| Alternative name 2: |
Clone: 64A6, IH/No WB, Mab antibody-Human, Mort-1, frozen/paraffin, Fas-Associated Death Domain Protein (FADD) |
| Alternative name 3: |
Clone: 64A6, IH/No WB, Mab antibody-Homo sapiens, Mort-1, frozen/paraffin, Fas-Associated Death Domain Protein (FADD) |
| Alternative name 4: |
anti-Fas-Associated Death Domain Protein FADD Mort-1 Clone: 64A6 No |
| Alternative name 5: |
Fas-Associated Death Domain Protein FADD Mort-1 Clone: 64A6 No |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
64A6, IH/No, Monoclonal frozen/paraffin, Fas-Associated Death Domain Protein (FADD) Mort-1 |
| Short name: |
Clone: 64A6, IH/No, Mouse Monoclonal antibody- frozen/paraffin, Fas-Associated Death Domain Protein (FADD) Mort-1 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, paraffin |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
-25°, IH/No Western Blot, Mort-1, Mouse monoclonal (Antibody to)-H, clonality: 64A6, member 6) (TNFRSF6)-associated via death domain), member 6)-Associated Death Domain Protein (Fas (TNF receptor superfamily, sapiens, C frozen/paraffin, Fas (TNF receptor superfamily |
| Alternative technique: |
murine |
| Alternative to gene target: |
FADD and IDBG-62144 and ENSG00000168040 and 8772, FADD and IDBG-645056 and ENSBTAG00000018274 and 493720, Fadd and IDBG-212910 and ENSMUSG00000031077 and 14082, MORT1, Plasma membranes, alpha-beta cytotoxic T cell extravasation and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001239 and regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, identical protein binding, this GO :0001916 and positive regulation of T cell mediated cytotoxicity and biological process this GO :0002020 and protease binding and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0002821 and positive regulation of adaptive immune response and biological process this GO :0005123 and death receptor binding and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007165 and signal transduction and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0016032 and viral process and biological process this GO :0031264 and death-inducing signaling complex and cellular component this GO :0031265 and CD95 death-inducing signaling complex and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0032813 and tumor necrosis factor receptor superfamily binding and molecular function this GO :0033077 and T cell differentiation in thymus and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035877 and death effector domain binding and molecular function this GO :0036462 and TRAIL-activated apoptotic signaling pathway and biological process this GO :0042104 and positive regulation of activated T cell proliferation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043005 and neuron projection and cellular component this GO :0043029 and T cell homeostasis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043234 and protein complex and cellular component this GO :0044297 and cell body and cellular component this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045651 and positive regulation of macrophage differentiation and biological process this GO :0045862 and positive regulation of proteolysis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048535 and lymph node development and biological process this GO :0048536 and spleen development and biological process this GO :0048538 and thymus development and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0051607 and defense response to virus and biological process this GO :0060340 and positive regulation of type I interferon-mediated signaling pathway and biological process this GO :0060546 and negative regulation of necroptotic process and biological process this GO :0070236 and negative regulation of activation-induced cell death of T cells and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0097049 and motor neuron apoptotic process and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :0097202 and activation of cysteine-type endopeptidase activity and biological process this GO :0097342 and ripoptosome and cellular component this GO :0097527 and necroptotic signaling pathway and biological process this GO :1902043 and positive regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000454 and positive regulation of CD8-positive, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0005123 : death receptor binding and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding and also this GO :0032403 : protein complex binding and also this GO :0032813 : tumor necrosis factor receptor superfamily binding and also this GO :0035877 : death effector domain binding and also this GO :0042802 : identical protein binding, this GO :0005123 : death receptor binding, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005515 : protein binding, this GO :0032403 : protein complex binding, this GO :0032813 : tumor necrosis factor receptor superfamily binding, this GO :0035877 : death effector domain binding, this GO :0042802 : identical protein binding, Fas (TNFRSF6)-associated via death domain |
| Identity: |
3573 |
| Gene: |
FADD |
More about : FADD |
| Long gene name: |
Fas associated via death domain |
| Synonyms gene name: |
Fas (TNFRSF6)-associated via death domain |
| Synonyms: |
MORT1 GIG3 |
| Synonyms name: |
Fas-associating protein with death domain Fas-associating death domain-containing protein mediator of receptor-induced toxicity growth-inhibiting gene 3 protein |
| Locus: |
11q13, 3 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
U24231 |
| Entrez gene record: |
8772 |
| Pubmed identfication: |
7536190 7538907 |
| RefSeq identity: |
NM_003824 |
| Classification: |
Death effector domain containing Ripoptosome Death inducing signaling complex |
| Havana BLAST/BLAT: |
OTTHUMG00000167264 |
| Locus Specific Databases: |
LRG_228 |