| Also known as: |
CD95 Ligand (biotin) |
| Other names: |
APTL, Apoptosis antigen ligand, CD95 ligand, CD95 ligand, CD95-L, CD_antigen: CD178Cleaved into the following 4 chains:Tumor necrosis factor ligand superfamily member 6, Fas antigen ligand, Fas ligand, Fas ligand (TNF superfamily, FasL, Soluble Fas ligand, Tumor necrosis factor ligand superfamily member 6, Tumor necrosis factor ligand superfamily member 6, apoptosis (APO-1) antigen ligand 1, apoptosis antigen ligand, fas antigen ligand, member 6, member 6), membrane form, sFasL, soluble formAlternative name(s):Receptor-binding FasL ectodomain, tumor necrosis factor (ligand) superfamily, tumor necrosis factor ligand superfamily member 6, CD95 ligand |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD95 Ligand |
| Other gene names: |
ALPS1B, APL, APT1LG1, APT1LG1, APTL, APTL, CD178, CD95-L, CD95-L, CD95L, CD95L, FASL, FASL, FASLG, Fas ligand, FasL, FasL ICD, SPA, TNFSF6, TNFSF6, sFasL, FASLG |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
MFL3 |
| Host organism: |
Hamster |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, N/A |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, Mouse |
| Form/Appearance: |
may contain carrier protein/stabilizer, 09% sodium azide, Supplied in aqueous buffer with 0 |
| Concentration: |
500 ug/ml |
| Storage and shipping: |
Keep the vial away from direct bright light, Variations in the range 1°, the antibody should NOT be frozen, C, C are tolerable, C to 9°, For short term storage keep the antibody at +4° |
| Tested applications:: |
Flow Cytometry (FC) |
| Description: |
Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling |
| French translation: |
anticorps |
| Gene target: |
CD95 Ligand |
| Short name: |
CD95 Ligand antibody (biotin) |
| Alternative name: |
CD95 Ligand (Antibody to) (biotinilated) |
| Alternative technique: |
antibodies |
| Identity: |
11920 |
| Gene: |
FAS |
More about : FAS |
| Long gene name: |
Fas cell surface death receptor |
| Synonyms gene: |
FAS1 APT1 TNFRSF6 |
| Synonyms gene name: |
member 6 Fas (TNF receptor superfamily, member 6) , tumor necrosis factor receptor superfamily |
| Synonyms: |
CD95 APO-1 |
| Synonyms name: |
TNF receptor superfamily member 6 |
| Locus: |
10q23, 31 |
| Discovery year: |
1992-06-25 |
| GenBank acession: |
M67454 |
| Entrez gene record: |
355 |
| Pubmed identfication: |
1385299 1385309 |
| Classification: |
CD molecules Tumor necrosis factor receptor superfamily Death inducing signaling complex |
| Havana BLAST/BLAT: |
OTTHUMG00000018701 |
| Locus Specific Databases: |
Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS LOVD at NCBI LRG_134 |