| Also known as: |
CD134 Ligand |
| Other names: |
CD134(OX40)-ligand, N/A, N/A, N/A, tumor necrosis factor ligand superfamily member 4, CD134(OX40)-ligand |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
N/A, N/A, N/A, TNFSF4 |
| Gene name synonims: |
N/A, N/A, N/A, TNFSF4 |
| Other gene names: |
N/A, N/A, N/A, TNFSF4 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
7H146 |
| Host organism: |
Mouse (Mus musculus) |
| Source organism: |
Human (Homo sapiens) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, and blocks binding of recombinant CD134-muIg, Binds to CD134L on the cell surface of HUVEC in Flow cytometry |
| Purification method: |
Affinity Purified by Protein A affinity chromatography |
| Form/Appearance: |
0, 0, 100mM potassium chloride, 150mM sodium chloride, 5% glycerol, Labeled with FITC, Molar Ratio: 8, 04% sodium azide, 1 FITC /IgG, 2% BSA, 5, Supplied as a liquid in 50mM sodium phosphate pH 7 |
| Storage and shipping: |
Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius, For long-term storage, For maximum recovery of product, For optimal long term storage, Further dilutions can be made in assay buffer, centrifuge the original vial after thawing and prior to removing the cap, the antibody should be kept at -20 degrees Celsius, Store the antibody at +4 degrees Celsius for short term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), ELISA (EL/EIA) |
| Properties: |
FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, MBS mono FITC is highly sensitive to pH extremes, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, This MBS mono Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS |
| Conjugation: |
Anti-FITC Antibody |
| Description: |
Receptor agonists are often tested for drug development, FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling |
| Gene target: |
CD252), OX40L, CD134 Ligand (CD134L |
| Short name: |
CD252) (FITC), OX40L, CD134 Ligand (CD134L |
| Technique: |
Fluorescein, FITC |
| Label: |
FITC |
| Alternative name: |
CD252) (fluorecein), OX40L, CD134 Ligand (CD134L |
| Alternative technique: |
fluorescine |
| Identity: |
11934 |
| Gene: |
TNFSF4 |
More about : TNFSF4 |
| Long gene name: |
tumor necrosis factor superfamily member 4 |
| Synonyms gene: |
TXGP1 |
| Synonyms gene name: |
34kD tumor necrosis factor (ligand) superfamily, member 4 , tax-transcriptionally activated glycoprotein 1 |
| Synonyms: |
OX-40L gp34 CD252 |
| Locus: |
1q25, 1 |
| Discovery year: |
1993-12-15 |
| GenBank acession: |
D90224 |
| Entrez gene record: |
7292 |
| Pubmed identfication: |
1996093 8076595 |
| Classification: |
Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000034838 |