| known also as: |
HsPEK, NT (Q163) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3, PEK, PERK), PRKR-like Endoplasmic Reticulum Kinase, Pancreatic eIF2-alpha Kinase, Anti-EIF2AK3 |
| known also as: |
HsPEK, NT (Q163) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3, PEK, PERK), PRKR-like Endoplasmic Reticulum Kinase, Pancreatic eIF2-alpha Kinase, EIF2AK3 |
| known also as: |
HsPEK, NT (Q163) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3, PEK, PERK), PRKR-like Endoplasmic Reticulum Kinase, Pancreatic eIF2-alpha Kinase, EIF2AK3 |
| known also as: |
EIF2AK3 |
| known also as: |
HsPEK, NT (Q163) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3, PEK, PERK), PRKR-like Endoplasmic Reticulum Kinase, Pancreatic eIF2-alpha Kinase, Anti -EIF2AK3 |
| Other names: |
Eukaryotic translation initiation factor 2-alpha kinase 3, OTTHUMP00000207186, OTTHUMP00000207187, OTTHUMP00000207188, PRKR-like endoplasmic reticulum kinase, PRKR-like endoplasmic reticulum kinase, Pancreatic eIF2-alpha kinase, eukaryotic translation initiation factor 2 alpha kinase 3, eukaryotic translation initiation factor 2-alpha kinase 3, eukaryotic translation initiation factor 2-alpha kinase 3, hsPEK, pancreatic EIF2-alpha kinase, eukaryotic translation initiation factor 2-alpha kinase 3 |
| Other gene names: |
DKFZp781H1925, EIF2AK3, PEK, PEK, PERK, PERK, WRS, EIF2AK3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Recognizes human PERK |
| Purification method: |
Purified by ammonium sulfate precipitation |
| Form/Appearance: |
0, 09% sodium azide, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquot to avoid repeated freezing and thawing, Aliquots are stable for at least 12 months, For maximum recovery of product, For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunohistochemistry (IHC), Western Blot (WB), ELISA (EL/EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
HsPEK, NT (Q163) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3, PEK, PERK), PRKR-like Endoplasmic Reticulum Kinase, Pancreatic eIF2-alpha Kinase, EIF2AK3 |
| Short name: |
HsPEK, NT (Q163) (Eukaryotic Translation Initiation Factor 2-alpha Kinase 3, PEK, PERK) Antibody, PRKR-like Endoplasmic Reticulum Kinase, Pancreatic eIF2-alpha Kinase, EIF2AK3 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HsPEK, NT (Q163) (Eukaryotic Translation Initiation Factor 2-a phosphorylation catalyst 3, PEK, PERK) (Antibody to), PRKR-like Endoplasmic Reticulum phosphorylation catalyst, Pancreatic eIF2-a phosphorylation catalyst, eukaryotic translation initiation factor 2-a phosphorylation catalyst 3 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
EIF2AK3 and IDBG-60518 and ENSG00000172071 and 9451, EIF2AK3 and IDBG-634760 and ENSBTAG00000000184 and 535820, Eif2ak3 and IDBG-155036 and ENSMUSG00000031668 and 13666, PEK and PERK and WRS, Plasma membranes, this GO :0001501 and skeletal system development and biological process this GO :0001503 and ossification and biological process this GO :0002063 and chondrocyte development and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004694 and eukaryotic translation initiation factor 2alpha kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005623 and cell and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006412 and translation and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0006983 and ER overload response and biological process this GO :0006987 and activation of signaling protein activity involved in unfolded protein response and biological process this GO :0007029 and endoplasmic reticulum organization and biological process this GO :0007595 and lactation and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004694 : eukaryotic translation initiation factor 2alpha kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004694 : eukaryotic translation initiation factor 2alpha kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019899 : enzyme binding, this GO :0019903 : protein phosphatase binding, this GO :0042802 : identical protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019899 : enzyme binding and also this GO :0019903 : protein phosphatase binding and also this GO :0042802 : identical protein binding, transferring phosphorus-containing groups and molecular function this GO :0017148 and negative regulation of translation and biological process this GO :0019217 and regulation of fatty acid metabolic process and biological process this GO :0019722 and calcium-mediated signaling and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0030073 and insulin secretion and biological process this GO :0030282 and bone mineralization and biological process this GO :0030968 and endoplasmic reticulum unfolded protein response and biological process this GO :0031016 and pancreas development and biological process this GO :0031018 and endocrine pancreas development and biological process this GO :0031642 and negative regulation of myelination and biological process this GO :0032055 and negative regulation of translation in response to stress and biological process this GO :0032057 and negative regulation of translational initiation in response to stress and biological process this GO :0032092 and positive regulation of protein binding and biological process this GO :0032933 and SREBP signaling pathway and biological process this GO :0034976 and response to endoplasmic reticulum stress and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048009 and insulin-like growth factor receptor signaling pathway and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0070059 and intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress and biological process, eukaryotic translation initiation factor 2-alpha kinase 3 |
| Identity: |
3255 |
| Gene: |
EIF2AK3 |
More about : EIF2AK3 |
| Long gene name: |
eukaryotic translation initiation factor 2 alpha kinase 3 |
| Synonyms: |
PEK PERK |
| Locus: |
2p11, 2 |
| Discovery year: |
1999-06-14 |
| GenBank acession: |
AF110146 |
| Entrez gene record: |
9451 |
| Pubmed identfication: |
10026192 10575235 |
| RefSeq identity: |
NM_004836 |
| Havana BLAST/BLAT: |
OTTHUMG00000155046 |
| Locus Specific Databases: |
LRG_1024 |