| known also as: |
HSD34, MGC35334, PRVTIRB, Proline-rich Vinculin and TIR Domain Containing Protein B, Putative NF-kappa-B-activating Protein 502H, Putative NFkB-activating Pr, TICAM1, TIR Domain Containing Adapter Molecule 1, Anti-TICAM-1 (Toll-like Receptor Adaptor Molecule 1 |
| known also as: |
HSD34, MGC35334, PRVTIRB, Proline-rich Vinculin and TIR Domain Containing Protein B, Putative NF-kappa-B-activating Protein 502H, Putative NFkB-activating Pr, TICAM1, TIR Domain Containing Adapter Molecule 1, TICAM-1 (Toll-like Receptor Adaptor Molecule 1 |
| known also as: |
HSD34, MGC35334, PRVTIRB, Proline-rich Vinculin and TIR Domain Containing Protein B, Putative NF-kappa-B-activating Protein 502H, Putative NFkB-activating Pr, TICAM1, TIR Domain Containing Adapter Molecule 1, TICAM-1 (Toll-like Receptor Adaptor Molecule 1 |
| known also as: |
TICAM-1 |
| known also as: |
HSD34, MGC35334, PRVTIRB, Proline-rich Vinculin and TIR Domain Containing Protein B, Putative NF-kappa-B-activating Protein 502H, Putative NFkB-activating Pr, TICAM1, TIR Domain Containing Adapter Molecule 1, Anti -TICAM-1 (Toll-like Receptor Adaptor Molecule 1 |
| Other names: |
Proline-rich, Putative NF-kappa-B-activating protein 502H, TIR domain containing adaptor inducing interferon-beta, TIR domain-containing adapter molecule 1, TIR domain-containing adapter molecule 1, TIR domain-containing adapter protein inducing IFN-beta, TIR domain-containing adaptor molecule 1, Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta, proline-rich, putative NF-kappa-B-activating protein 502H, toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta, toll-like receptor adaptor molecule 1, vinculin and TIR domain-containing protein B, vinculin and TIR domain-containing protein B, TIR domain-containing adapter molecule 1 |
| Other gene names: |
MGC35334, PRVTIRB, PRVTIRB, TICAM-1, TICAM1, TRIF, TRIF, TICAM1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Mouse, Host: Rabbit |
| Species reactivity: |
Mouse, Rat, Human |
| Specificity and cross-reactivity: |
Mouse and Rat, Species Crossreactivity: Crossreacts with Human, but additional bands may be seen, The antibody will crossreact with human TICAM |
| Purification method: |
Serum Whole antisera |
| Form/Appearance: |
0, 0, 05% sodium azide, 2% gelatin, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquots are stable for at least 3 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, add sterile glycerol (40-50%), aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB) |
| Description: |
present in lysates used as reference for ELISA quantification of these molecules and their subunits, Whole adhesion and interacting molecules are  |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
HSD34, MGC35334, PRVTIRB, Proline-rich Vinculin TIR Domain Protein B, Putative NF-kappa-B-activating Protein 502H, Putative NFkB-activating Pr, TICAM1, TIR Domain Adapter Molecule 1, TICAM-1 (Toll-like Receptor Adaptor Molecule 1 |
| Short name: |
HSD34, MGC35334, PRVTIRB, Proline-rich Vinculin TIR Domain Protein B, Putative NF-kappa-B-activating Protein 502H, Putative NFkB-activating Pr, TICAM1, TIR Domain Adapter Molecule 1, TICAM-1 (Toll-like Receptor Adaptor Molecule 1 |
| Alternative name: |
HSD34, MGC35334, PRVTIRB, Proline-rich Vinculin and TIR Domain Containing Protein B, Putative NF-kappa-B-activating Protein 502H, Putative NFkB-activating Pr, TIR Domain Containing Adapter Molecule 1, toll-like receptor adaptor molecule 1, TICAM-1 (Toll-like Receptor Adaptor Molecule 1 |
| Alternative to gene target: |
BT, Cytoplasm, TICAM1 and IDBG-19505 and ENSG00000127666 and 148022, Ticam1 and IDBG-191912 and ENSMUSG00000047123 and 106759, protein kinase binding, this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002281 and macrophage activation involved in immune response and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0010008 and endosome membrane and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0032092 and positive regulation of protein binding and biological process this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0032816 and positive regulation of natural killer cell activation and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043330 and response to exogenous dsRNA and biological process this GO :0043496 and regulation of protein homodimerization activity and biological process this GO :0045080 and positive regulation of chemokine biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045359 and positive regulation of interferon-beta biosynthetic process and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0050871 and positive regulation of B cell activation and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051607 and defense response to virus and biological process this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097342 and ripoptosome and cellular component, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, 47460 and IDBG-644220 and ENSBTAG00000019966 and 510427, toll-like receptor adaptor molecule 1 |
| Identity: |
18348 |
| Gene: |
TICAM1 |
More about : TICAM1 |
| Long gene name: |
toll like receptor adaptor molecule 1 |
| Synonyms gene name: |
toll-like receptor adaptor molecule 1 |
| Synonyms: |
TRIF TICAM-1 MGC35334 PRVTIRB |
| Synonyms name: |
TIR domain-containing adapter molecule 1 |
| Locus: |
19p13, 3 |
| Discovery year: |
2005-06-27 |
| GenBank acession: |
AB086380 |
| Entrez gene record: |
148022 |
| Pubmed identfication: |
12539043 12471095 |
| RefSeq identity: |
NM_014261 |
| Classification: |
TIR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180248 |
| Locus Specific Databases: |
LRG_358 |