| known also as: |
CT (Single Ig IL-1-Related Receptor, Single Ig IL-1R-Related Molecule, Single Immunoglobulin Domain-Containing IL1R-Related Protein, TIR8), Toll/Interleukin-1 Receptor 8, Anti-SIGIRR |
| known also as: |
CT (Single Ig IL-1-Related Receptor, Single Ig IL-1R-Related Molecule, Single Immunoglobulin Domain-Containing IL1R-Related Protein, TIR8), Toll/Interleukin-1 Receptor 8, SIGIRR |
| known also as: |
CT (Single Ig IL-1-Related Receptor, Single Ig IL-1R-Related Molecule, Single Immunoglobulin Domain-Containing IL1R-Related Protein, TIR8), Toll/Interleukin-1 Receptor 8, SIGIRR |
| known also as: |
SIGIRR |
| known also as: |
CT (Single Ig IL-1-Related Receptor, Single Ig IL-1R-Related Molecule, Single Immunoglobulin Domain-Containing IL1R-Related Protein, TIR8), Toll/Interleukin-1 Receptor 8, Anti -SIGIRR |
| Other names: |
OTTHUMP00000229641, OTTHUMP00000229642, OTTHUMP00000229643, OTTHUMP00000229644, OTTHUMP00000229645, Single Ig IL-1-related receptor, Single Ig IL-1R-related molecule, Single immunoglobulin domain-containing IL1R-related protein, Toll/interleukin-1 receptor 8, single Ig IL-1-related receptor, single Ig IL-1R-related molecule, single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, single immunoglobulin domain IL1R1 related, single immunoglobulin domain-containing IL1R-related protein, toll/interleukin-1 receptor 8, single Ig IL-1-related receptor |
| Other gene names: |
MGC110992, N/A, SIGIRR, TIR8, SIGIRR |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Mouse, Host: Rabbit |
| Species reactivity: |
Mouse, Human |
| Specificity and cross-reactivity: |
Species Crossreactivity: human, Recognizes mouse SIGIRR at ~43kD in A549 cell lysate |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
0, 02% sodium azide, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquot to avoid repeated freezing and thawing, Aliquots are stable for at least 12 months, For maximum recovery of product, For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunohistochemistry (IHC), Western Blot (WB) |
| Description: |
present in lysates used as reference for ELISA quantification of these molecules and their subunits, Whole adhesion and interacting molecules are  |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene: |
SIGIRR |
More about : SIGIRR |
| Gene target: |
CT (Single Ig IL-1-Related Receptor, Single Ig IL-1R-Related Molecule, Single Immunoglobulin Domain IL1R-Related Protein, TIR8), Toll/Interleukin-1 Receptor 8, SIGIRR |
| Short name: |
CT (Single Ig IL-1- Receptor, Single Ig IL-1R- Molecule, Single Immunoglobulin Domain- IL1R- Protein, TIR8), Toll/Interleukin-1 Receptor 8, SIGIRR |
| Alternative name: |
CT (Single Ig Interleukin-1-Related Receptor, Single Ig Interleukin-1R-Related Molecule, Single Immunoglobulin Domain-Containing IL1R-Related Protein, TIR8), Toll/Interleukin-1 Receptor 8, single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| Alternative to gene target: |
Plasma membranes, SIGIRR and IDBG-16551 and ENSG00000185187 and 59307, SIGIRR and IDBG-645604 and ENSBTAG00000011149 and 531801, Sigirr and IDBG-211977 and ENSMUSG00000025494 and 24058, protein binding, this GO :0001960 and negative regulation of cytokine-mediated signaling pathway and biological process this GO :0005515 and protein binding and molecular function this GO :0006953 and acute-phase response and biological process this GO :0007165 and signal transduction and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0031665 and negative regulation of lipopolysaccharide-mediated signaling pathway and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0045079 and negative regulation of chemokine biosynthetic process and biological process this GO :0045087 and innate immune response and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| Identity: |
30575 |
| Long gene name: |
single Ig and TIR domain containing |
| Synonyms gene name: |
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| Synonyms: |
TIR8 IL-1R8 |
| Synonyms name: |
single immunoglobulin domain IL1R1 related |
| Locus: |
11p15, 5 |
| Discovery year: |
2005-10-10 |
| Entrez gene record: |
59307 |
| Pubmed identfication: |
10346978 |
| RefSeq identity: |
NM_021805 |
| Classification: |
Immunoglobulin like domain containing TIR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000165412 |