| known also as: |
COCA2, Colon Cancer Type 2, DNA Mismatch Repair Protein Mlh1, FCC2, Familial Nonpolyposis Colin Cancer Type 2, HNPCC, HNPCC2, MGC5172, MutL Homolog 1, MutL Homolog 1 Colon Cancer Nonpolyposis Type 2, MutL Protein Homolog, hMLH1, Anti-MLH1 (Human Mul L Homolog |
| known also as: |
COCA2, Colon Cancer Type 2, DNA Mismatch Repair Protein Mlh1, FCC2, Familial Nonpolyposis Colin Cancer Type 2, HNPCC, HNPCC2, MGC5172, MutL Homolog 1, MutL Homolog 1 Colon Cancer Nonpolyposis Type 2, MutL Protein Homolog, hMLH1, MLH1 (Human Mul L Homolog |
| known also as: |
COCA2, Colon Cancer Type 2, DNA Mismatch Repair Protein Mlh1, FCC2, Familial Nonpolyposis Colin Cancer Type 2, HNPCC, HNPCC2, MGC5172, MutL Homolog 1, MutL Homolog 1 Colon Cancer Nonpolyposis Type 2, MutL Protein Homolog, hMLH1, MLH1 (Homo sapiens Mul L Homolog |
| known also as: |
MLH1 |
| known also as: |
COCA2, Colon Cancer Type 2, DNA Mismatch Repair Protein Mlh1, FCC2, Familial Nonpolyposis Colin Cancer Type 2, HNPCC, HNPCC2, MGC5172, MutL Homolog 1, MutL Homolog 1 Colon Cancer Nonpolyposis Type 2, MutL Protein Homolog, hMLH1, Anti -MLH1 (Human Mul L Homolog |
| Other names: |
CG11482 gene product from transcript CG11482-RA, CG11482-PA, Mlh1, Mlh1-PA, N/A, N/A, N/A, Mlh1 |
| Other gene names: |
CG11482, DmelCG11482, N/A, N/A, dmlh-1, dmlh1, Mlh1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Specific for human MLH1 |
| Purification method: |
As reported |
| Storage and shipping: |
Aliquots are stable for at least 6 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunoprecipitation (IP) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| Gene target: |
COCA2, Colon Cancer 2, DNA Mismatch Repair Protein Mlh1, FCC2, Familial Nonpolyposis Colin Cancer 2, HNPCC, HNPCC2, MGC5172, MutL Homolog 1, MutL Homolog 1 Colon Cancer Nonpolyposis 2, MutL Protein Homolog, hMLH1, MLH1 Mul L Homolog |
| Short name: |
COCA2, Colon Cancer 2, DNA Mismatch Repair Protein Mlh1, FCC2, Familial Nonpolyposis Colin Cancer 2, HNPCC, HNPCC2, MGC5172, MutL Homolog 1, MutL Homolog 1 Colon Cancer Nonpolyposis 2, MutL Protein Homolog Antibody, hMLH1, MLH1 ( Mul L Homolog |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Species: |
Humans, Human |
| Alternative name: |
COCA2, Colon Cancer classification 2, Desoxyribonucleic acid Mismatch Repair Protein mutL homolog 1, FCC2, Familial Nonpolyposis Colin Cancer classification 2, HNPCC, HNPCC2, MGC5172, MutL Homolog 1, MutL Homolog 1 Colon Cancer Nonpolyposis classification 2, MutL Protein Homolog (Antibody to), coli), coli) (H, colon cancer, colon cancer, hMLH1, nonpolyposis classification 2 (E, nonpolyposis classification 2 (E, sapiens Mul L Homolog, mutL homolog 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
COCA2 and FCC2 and hMLH1 and HNPCC and HNPCC2, MLH1 and IDBG-24600 and ENSG00000076242 and 4292, MLH1 and IDBG-644253 and ENSBTAG00000016758 and 533652, Mlh1 and IDBG-202755 and ENSMUSG00000032498 and 17350, coli), colon cancer, nonpolyposis type 2 (E, nuclei, structure-specific DNA binding, this GO :0000289 and nuclear-transcribed mRNA poly(A) tail shortening and biological process this GO :0000712 and resolution of meiotic recombination intermediates and biological process this GO :0000793 and condensed chromosome and cellular component this GO :0000794 and condensed nuclear chromosome and cellular component this GO :0000795 and synaptonemal complex and cellular component this GO :0001673 and male germ cell nucleus and cellular component this GO :0002204 and somatic recombination of immunoglobulin genes involved in immune response and biological process this GO :0003697 and single-stranded DNA binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005694 and chromosome and cellular component this GO :0005712 and chiasma and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006281 and DNA repair and biological process this GO :0006298 and mismatch repair and biological process this GO :0006303 and double-strand break repair via nonhomolo this GO us end joining and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007060 and male meiosis chromosome segregation and biological process this GO :0007129 and synapsis and biological process this GO :0007131 and reciprocal meiotic recombination and biological process this GO :0007140 and male meiosis and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0016020 and membrane and cellular component this GO :0016446 and somatic hypermutation of immunoglobulin genes and biological process this GO :0016447 and somatic recombination of immunoglobulin gene segments and biological process this GO :0016887 and ATPase activity and molecular function this GO :0030983 and mismatched DNA binding and molecular function this GO :0032137 and guanine/thymine mispair binding and molecular function this GO :0032300 and mismatch repair complex and cellular component this GO :0032389 and MutLalpha complex and cellular component this GO :0032407 and MutSalpha complex binding and molecular function this GO :0043060 and meiotic metaphase I plate congression and biological process this GO :0043566 and structure-specific DNA binding and molecular function this GO :0045132 and meiotic chromosome segregation and biological process this GO :0045190 and isotype switching and biological process this GO :0045950 and negative regulation of mitotic recombination and biological process this GO :0048477 and oogenesis and biological process this GO :0051257 and spindle midzone assembly involved in meiosis and biological process, this GO :0003697 : single-stranded DNA binding, this GO :0003697 : single-stranded DNA binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016887 : ATPase activity and also this GO :0030983 : mismatched DNA binding and also this GO :0032137 : guanine/thymine mispair binding and also this GO :0032407 : MutSalpha complex binding and also this GO :0043566 : structure-specific DNA binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016887 : ATPase activity, this GO :0030983 : mismatched DNA binding, this GO :0032137 : guanine/thymine mispair binding, this GO :0032407 : MutSalpha complex binding, this GO :0043566 : structure-specific DNA binding, mutL homolog 1 |
| Identity: |
7127 |
| Gene: |
MLH1 |
More about : MLH1 |
| Long gene name: |
mutL homolog 1 |
| Synonyms gene: |
COCA2 |
| Synonyms gene name: |
coli) , coli) homolog 1 (colon cancer, colon cancer, mutL (E, nonpolyposis type 2 (E, nonpolyposis type 2) mutL homolog 1 |
| Synonyms: |
HNPCC FCC2 HNPCC2 |
| Locus: |
3p22, 2 |
| Discovery year: |
1993-11-24 |
| GenBank acession: |
U07418 |
| Entrez gene record: |
4292 |
| Pubmed identfication: |
7903889 |
| RefSeq identity: |
NM_000249 |
| Classification: |
MutL homologs |
| Havana BLAST/BLAT: |
OTTHUMG00000130797 |
| Locus Specific Databases: |
HNPCC Colon cancer gene variant databases MLH1 database at LOVD-China LOVD - Leiden Open Variation Database LRG_216 , Hereditary Non-Polyposis Colorectal Cancer |