| Also known as: |
MLL |
| Other names: |
ALL-1, Alternative name(s):, Alternative name(s):, C-terminal cleavage product of 180 kDa, CDK6/MLL fusion protein, CXXC-type zinc finger protein 7, CXXC-type zinc finger protein 7, Drosophila), Histone-lysine N-methyltransferase MLL, KMT2A, Lysine N-methyltransferase 2A, MLL-AF4 der(11) fusion protein, MLL/GAS7 fusion protein, MLL/GMPS fusion protein, N-terminal cleavage product of 320 kDa, Trithorax-like protein, Zinc finger protein HRXCleaved into the following 2 chains:MLL cleavage product N320, histone-lysine N-methyltransferase MLL, lysine N-methyltransferase 2A, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, p320MLL cleavage product C180, trithorax-like protein, zinc finger protein HRX, MLL |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
MLL |
| Other gene names: |
ALL-1, ALL1, CXXC7, CXXC7, HRX, HRX, HTRX, HTRX1, KMT2A, KMT2A, KMT2A, MLL, MLL/GAS7, MLL1, MLL1A, TET1-MLL, TRX1, TRX1, p180, p320, MLL |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
10F8D7 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, N/A |
| Form/Appearance: |
03% sodium azide, Supplied as a liquid in ascitic fluid containing 0 |
| Concentration: |
0 mg/ml, 1 |
| Storage and shipping: |
Avoid repeated freeze/thaw cycles, Store at -20 deg C for long term storage, Temperature variations in the range 1°, for short term storage, keep the antibody at +4°, C, C are tolerable, C to 9°, For optimal storage conditions |
| Tested applications:: |
Immunohistochemistry (IHC), Western Blot (WB), ELISA (EIA) |
| French translation: |
anticorps |
| Gene target: |
MLL |
| Short name: |
MLL antibody |
| Alternative name: |
Drosophila) (Antibody to), myeloid/lymphoid and mixed-lineage leukemia (trithorax homolog |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ALL-1 and CXXC7 and HRX and HTRX1 and MLL and MLL/GAS7 and MLL1 and MLL1A and TET1-MLL and TRX1 and WDSTS, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0032411 and positive regulation of transporter activity and biological process this GO :0035097 and histone methyltransferase complex and cellular component this GO :0035162 and embryonic hemopoiesis and biological process this GO :0042800 and histone methyltransferase activity (H3-K4 specific) and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0042803 and protein homodimerization activity and molecular function this GO :0043984 and histone H4-K16 acetylation and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045322 and unmethylated CpG binding and molecular function this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0051568 and histone H3-K4 methylation and biological process this GO :0051569 and regulation of histone H3-K4 methylation and biological process this GO :0070577 and lysine-acetylated histone binding and molecular function this GO :0071339 and MLL1 complex and cellular component this GO :0080182 and histone H3-K4 trimethylation and biological process this GO :2001040 and positive regulation of cellular response to drug and biological process, Drosophila), MLL and IDBG-631302 and ENSBTAG00000018093 and 508330, MLL and IDBG-73725 and ENSG00000118058 and 4297, Mll1 and IDBG-158453 and ENSMUSG00000002028 and 214162, lysine-acetylated histone binding, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0003680 and AT DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006306 and DNA methylation and biological process this GO :0006355 and regulation of transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003680 : AT DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0042800 : histone methyltransferase activity (H3-K4 specific) and also this GO :0042802 : identical protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0045322 : unmethylated CpG binding and also this GO :0070577 : lysine-acetylated histone binding, this GO :0003680 : AT DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0042800 : histone methyltransferase activity (H3-K4 specific), this GO :0042802 : identical protein binding, this GO :0042803 : protein homodimerization activity, this GO :0044212 : transcription regulatory region DNA binding, this GO :0045322 : unmethylated CpG binding, this GO :0070577 : lysine-acetylated histone binding, myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog |
| Identity: |
7132 |
| Gene: |
KMT2A |
More about : KMT2A |
| Long gene name: |
lysine methyltransferase 2A |
| Synonyms gene: |
MLL |
| Synonyms gene name: |
Drosophila) lysine (K)-specific methyltransferase 2A , myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog) myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog |
| Synonyms: |
TRX1 HRX ALL-1 HTRX1 CXXC7 MLL1A |
| Locus: |
11q23, 3 |
| Discovery year: |
1991-11-15 |
| GenBank acession: |
L04284 |
| Entrez gene record: |
4297 |
| Pubmed identfication: |
1720549 |
| RefSeq identity: |
NM_005933 |
| Classification: |
PHD finger proteins Lysine methyltransferases Zinc fingers CXXC-type |
| Havana BLAST/BLAT: |
OTTHUMG00000166337 |
| Locus Specific Databases: |
LRG_613 |