| known also as: |
DKFZP781H1425), DYS, ELP1, FD, FLJ12497, IKAP, IKBKAP, IKI3, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-cells, Kinase Complex-associated Protein, P150, TOT1, Anti-Elongator Protein 1 (ELP1 |
| known also as: |
DKFZP781H1425), DYS, ELP1, FD, FLJ12497, IKAP, IKBKAP, IKI3, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-cells, Kinase Complex-associated Protein, P150, TOT1, Elongator Protein 1 (ELP1 |
| known also as: |
DKFZP781H1425), DYS, ELP1, FD, FLJ12497, IKAP, IKBKAP, IKI3, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-cells, Kinase Complex-associated Protein, P150, TOT1, Elongator Protein 1 (ELP1 |
| known also as: |
Elongator Protein 1 |
| known also as: |
DKFZP781H1425), DYS, ELP1, FD, FLJ12497, IKAP, IKBKAP, IKI3, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-cells, Kinase Complex-associated Protein, P150, TOT1, Anti -Elongator Protein 1 (ELP1 |
| Other names: |
Elongator complex protein 1, IKK complex-associated protein, IKK complex-associated protein, IkappaB kinase complex-associated protein, OTTHUMP00000021869, elongator complex protein 1, ikappaB kinase complex-associated protein, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein, p150, p150, elongator complex protein 1 |
| Other gene names: |
DKFZp781H1425, DYS, ELP1, ELP1, FD, FLJ12497, IKAP, IKAP, IKBKAP, IKI3, TOT1, IKBKAP |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Mouse, Human |
| Specificity and cross-reactivity: |
IKBKAP was originally described as a scaffold protein of the IKK complex involved in NF-kB activation, Species Crossreactivity: mouse, but this role has since been disputed, Recognizes human IKBKAP |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
0, 02% sodium azide, Supplied as a liquid in PBS |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB) |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
DKFZP781H1425), DYS, ELP1, FD, FLJ12497, IKAP, IKBKAP, IKI3, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-cells, Kinase Complex-associated Protein, P150, TOT1, Elongator Protein 1 (ELP1 |
| Short name: |
DKFZP781H1425) Antibody, DYS, ELP1, FD, FLJ12497, IKAP, IKBKAP, IKI3, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B-cells, Kinase Complex-associated Protein, P150, TOT1, Elongator Protein 1 (ELP1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DKFZP781H1425) (Antibody to), DYS, ELP1, FD, FLJ12497, IKAP, IKI3, P150, TOT1, inhibitor on kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein, phosphorylation catalyst aggregate-associated Protein, suppressor on Kappa Light multipeptide Gene Enhancer In B-cells, Elongator Protein 1 (ELP1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DYS and ELP1 and FD and IKAP and IKI3 and TOT1, IKBKAP and IDBG-637400 and ENSBTAG00000004991 and 505465, IKBKAP and IDBG-79889 and ENSG00000070061 and 8518, Ikbkap and IDBG-148849 and ENSMUSG00000028431 and 230233, holoenzyme and cellular component this GO :0030335 and positive regulation of cell migration and biological process this GO :0033588 and Elongator holoenzyme complex and cellular component this GO :0045859 and regulation of protein kinase activity and biological process, kinase complex-associated protein, nuclei, phosphorylase kinase regulator activity, this GO :0003677 and DNA binding and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005730 and nucleolus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006325 and chromatin organization and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006368 and transcription elongation from RNA polymerase II promoter and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006955 and immune response and biological process this GO :0007165 and signal transduction and biological process this GO :0008023 and transcription elongation factor complex and cellular component this GO :0008607 and phosphorylase kinase regulator activity and molecular function this GO :0016591 and DNA-directed RNA polymerase II, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0004871 : signal transducer activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0008607 : phosphorylase kinase regulator activity, this GO :0004871 : signal transducer activity, this GO :0005488 : binding, this GO :0005515 : protein binding, this GO :0008607 : phosphorylase kinase regulator activity, inhibitor of kappa light polypeptide gene enhancer in B-cells |
| Identity: |
5959 |
| Gene: |
IKBKAP |
More about : IKBKAP |
| Long gene name: |
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| Synonyms gene: |
DYS |
| Synonyms gene name: |
dysautonomia (Riley-Day syndrome, hereditary sensory autonomic neuropathy type III) |
| Synonyms: |
IKAP TOT1 ELP1 IKI3 |
| Synonyms name: |
elongator acetyltransferase complex subunit 1 |
| Locus: |
9q31, 3 |
| Discovery year: |
1998-09-30 |
| GenBank acession: |
AF044195 |
| Entrez gene record: |
8518 |
| Pubmed identfication: |
9751059 11179008 |
| Classification: |
Elongator acetyltransferase complex |
| Havana BLAST/BLAT: |
OTTHUMG00000020465 |
| Locus Specific Databases: |
Inherited Peripheral Neuropathies Mutation Database LRG_251 |