| known also as: |
phosphorylated (Ser199, 197), 2, 204) (Ser192, Anti-PAK1 |
| known also as: |
phosphorylated (Ser199, 197), 2, 204) (Ser192, PAK1 |
| known also as: |
phosphorylated (Ser199, 197), 2, 204) (Ser192, PAK1 |
| known also as: |
2, PAK1 |
| known also as: |
phosphorylated (Ser199, 197), 2, 204) (Ser192, Anti -PAK1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Human, Mouse, Rat, Guinea Pig |
| Specificity and cross-reactivity: |
It may also detect Ser200/205 phosphorylated PAK3, MAPK signaling, Species Crossreactivity: Human and guinea pig, The p21-activated kinase (PAK) family of serine/threonine kinases is engaged in multiple cellular processes, apoptotic signaling, control of phagocyte NADPH oxidase and growth factor-induced neurite outgrowth, however it does not cross-react with phosphorylated PAK4, including cytoskeletal reorganization, predicted to react with rat and mouse due to 100% sequence homology, Recognizes Ser199/204 phosphorylated PAK1 or Ser192/197 phosphorylated PAK2 |
| Purification method: |
Affinity Purified by Protein A affinity chromatography |
| Form/Appearance: |
100ug/ml BSA, 150 mM sodium chloride, 50% glycerol, pH 7, 5, Supplied as a liquid in 10mM HEPES |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Freeze productone should be stored at -20 degrees Celsius, Further dilutions can be made in assay buffer, aliquot and add glycerol (30-50%), centrifuge the original vial after thawing and prior to removing the cap, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
phosphorylated (Ser199, 197), 2, 204) (Ser192, PAK1 |
| Short name: |
phosphorylated (Ser199, 197) Antibody, 2, 204) (Ser192, PAK1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
phosphorylated (Ser199, 197) (Antibody to), 2, 204) (Ser192, p21 protein (Cdc42/Rac)-activated kinase 1 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
PAK1 and IDBG-642220 and ENSBTAG00000010191 and 533729, PAK1 and IDBG-65610 and ENSG00000149269 and 5058, PAKalpha, Pak1 and IDBG-199974 and ENSMUSG00000030774 and 18479, nuclei, this GO :0001666 and response to hypoxia and biological process this GO :0001726 and ruffle and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006887 and exocytosis and biological process this GO :0006915 and apoptotic process and biological process this GO :0007015 and actin filament organization and biological process this GO :0007411 and axon guidance and biological process this GO :0007528 and neuromuscular junction development and biological process this GO :0010033 and response to organic substance and biological process this GO :0014704 and intercalated disc and cellular component this GO :0016020 and membrane and cellular component this GO :0016358 and dendrite development and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005518 : collagen binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005518 : collagen binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019901 : protein kinase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901 : protein kinase binding, transferring phosphorus-containing groups and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030018 and Z disc and cellular component this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0030426 and growth cone and cellular component this GO :0031295 and T cell costimulation and biological process this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0031941 and filamentous actin and cellular component this GO :0031965 and nuclear membrane and cellular component this GO :0032587 and ruffle membrane and cellular component this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0033148 and positive regulation of intracellular estrogen receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042060 and wound healing and biological process this GO :0043113 and receptor clustering and biological process this GO :0043234 and protein complex and cellular component this GO :0043507 and positive regulation of JUN kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0048812 and neuron projection morphogenesis and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051496 and positive regulation of stress fiber assembly and biological process this GO :0060244 and negative regulation of cell proliferation involved in contact inhibition and biological process, p21 protein (Cdc42/Rac)-activated kinase 1 |
| Identity: |
8590 |
| Gene: |
PAK1 |
More about : PAK1 |
| Long gene name: |
p21 (RAC1) activated kinase 1 |
| Synonyms gene name: |
p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) p21 protein (Cdc42/Rac)-activated kinase 1 |
| Synonyms name: |
STE20 homolog, yeast |
| Locus: |
11q13, 1 , 5-q14 |
| Discovery year: |
1997-12-05 |
| GenBank acession: |
U51120 |
| Entrez gene record: |
5058 |
| Pubmed identfication: |
8805275 9533029 |
| RefSeq identity: |
NM_002576 |
| Havana BLAST/BLAT: |
OTTHUMG00000165138 |