| known also as: |
HIV-1 Nef-interacting Protein, KIAA0113, Naf1, Nef-associated Factor 1, Nip40-1, TNFAIP3 Interacting Protein 1, TNIP1, VAN, Virion-associated Nuclear Shuttling Protein, hVAN), Anti-ABIN-1 (A-20 Binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation |
| known also as: |
HIV-1 Nef-interacting Protein, KIAA0113, Naf1, Nef-associated Factor 1, Nip40-1, TNFAIP3 Interacting Protein 1, TNIP1, VAN, Virion-associated Nuclear Shuttling Protein, hVAN), ABIN-1 (A-20 Binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation |
| known also as: |
HIV-1 Nef-interacting Protein, KIAA0113, Naf1, Nef-associated Factor 1, Nip40-1, TNFAIP3 Interacting Protein 1, TNIP1, VAN, Virion-associated Nuclear Shuttling Protein, hVAN), ABIN-1 (A-20 Binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation |
| known also as: |
ABIN-1 |
| known also as: |
HIV-1 Nef-interacting Protein, KIAA0113, Naf1, Nef-associated Factor 1, Nip40-1, TNFAIP3 Interacting Protein 1, TNIP1, VAN, Virion-associated Nuclear Shuttling Protein, hVAN), Anti -ABIN-1 (A-20 Binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation |
| Other names: |
A20 binding and inhibitor of NF-kB protein 1, N/A, N/A, N/A, Nef-associated factor 1, TNFAIP3-interacting protein 1, A20 binding and inhibitor of NF-kB protein 1 |
| Other gene names: |
N/A, N/A, NAF1, TNIP1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Mouse, Rat, Human |
| Specificity and cross-reactivity: |
Species Crossreactivity, Recognizes endogenous levels of human total ABIN-1 protein |
| Purification method: |
Affinity Purified by Protein A and peptide affinity chromatography |
| Form/Appearance: |
0, 150mM NaCl, 50% glycerol, 1mg/ml BSA, 5, Supplied as a liquid in 10mM sodium HEPES pH 7 |
| Storage and shipping: |
Aliquot to avoid repeated freezing and thawing, Aliquots are stable for at least 12 months, For maximum recovery of product, For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunoprecipitation (IP), Western Blot (WB) |
| Description: |
Not all receptor antagonist that bind to enzymes are inhibitors, Since blocking an enzyme's activity can kill a pathogen , activator, caspase, esterase inhibitors , lipoprotein, many drugs are enzyme inhibitors, papain, pathway, peptidase, protease , proteinase, trypsin, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme, , Tissue, acrosin, activity, and decreases its , are , bind to enzymes and increase their , enzymatic activity, enzyme activator ligands or agonists , enzyme receptor , imbalance, metabolic , or correct a , or receptor ligands or receptor antagonists that bind to an , proteins |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene: |
TNIP1 |
More about : TNIP1 |
| Gene target: |
HIV-1 Nef-interacting Protein, KIAA0113, Naf1, Nef-associated Factor 1, Nip40-1, TNFAIP3 Interacting Protein 1, TNIP1, VAN, Virion-associated Shuttling Protein, hVAN), ABIN-1 (A-20 Binding Inhibitor of Factor-kappaB (NF-kB) Activation |
| Short name: |
HIV-1 Nef-interacting Protein, KIAA0113, Naf1, Nef-associated Factor 1, Nip40-1, TNFAIP3 Interacting Protein 1, TNIP1, VAN, Virion-associated Nuclear Shuttling Protein, hVAN) Antibody, ABIN-1 (A-20 Binding Inhibitor of Nuclear Factor-kappaB (NF-kB) Activation |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
KIAA0113, Naf1, Nef-associated Factor 1, Nip40-1, TNFAIP3 interacting protein 1, VAN, Virion-associated Nuclear Shuttling Protein, a-induced protein 3 Interacting Protein 1, hVAN) (Antibody to), human immunodeficiency virus-1 Nef-interacting Protein, tumor necrosis factor, ABIN-1 (A-20 Binding suppressor on Nuclear Factor-kappaB (NF-kB) Activation |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
A20 and OTUD7C and TNFA1P2, ABIN-1 and NAF1 and nip40-1 and VAN, TNFAIP3 and IDBG-633691 and ENSBTAG00000000436 and 508105, TNFAIP3 and IDBG-97033 and ENSG00000118503 and 7128, TNIP1 and IDBG-54098 and ENSG00000145901 and 10318, TNIP1 and IDBG-646318 and ENSBTAG00000012671 and 526103, Tnfaip3 and IDBG-135792 and ENSMUSG00000019850 and 21929, Tnip1 and IDBG-174207 and ENSMUSG00000020400 and 57783, alpha-induced protein 3, leucine rich repeat containing receptor signaling pathway and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043130 and ubiquitin binding and molecular function this GO :0043621 and protein self-association and molecular function this GO :0045087 and innate immune response and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045779 and negative regulation of bone resorption and biological process this GO :0045824 and negative regulation of innate immune response and biological process this GO :0048662 and negative regulation of smooth muscle cell proliferation and biological process this GO :0050691 and regulation of defense response to virus by host and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050869 and negative regulation of B cell activation and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0060548 and negative regulation of cell death and biological process this GO :0061043 and regulation of vascular wound healing and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0070429 and negative regulation of nucleotide-binding oli this GO merization domain containing 1 signaling pathway and biological process this GO :0070433 and negative regulation of nucleotide-binding oli this GO merization domain containing 2 signaling pathway and biological process this GO :0070536 and protein K63-linked deubiquitination and biological process this GO :0070936 and protein K48-linked ubiquitination and biological process this GO :0071108 and protein K48-linked deubiquitination and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0072573 and tolerance induction to lipopolysaccharide and biological process this GO :0090291 and negative regulation of osteoclast proliferation and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000347 and positive regulation of hepatocyte proliferation and biological process this GO :2000349 and negative regulation of CD40 signaling pathway and biological process this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process, mitogen-activated protein kinase binding, nuclei, nuclei, protein self-association, this GO :0001922 and B-1 B cell homeostasis and biological process this GO :0002020 and protease binding and molecular function this GO :0002237 and response to molecule of bacterial origin and biological process this GO :0002634 and regulation of germinal center formation and biological process this GO :0002677 and negative regulation of chronic inflammatory response and biological process this GO :0003677 and DNA binding and molecular function this GO :0004221 and ubiquitin thiolesterase activity and molecular function this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0004843 and ubiquitin-specific protease activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016579 and protein deubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0019900 and kinase binding and molecular function this GO :0031397 and negative regulation of protein ubiquitination and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032495 and response to muramyl dipeptide and biological process this GO :0032691 and negative regulation of interleukin-1 beta production and biological process this GO :0032703 and negative regulation of interleukin-2 production and biological process this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0034136 and negative regulation of toll-like receptor 2 signaling pathway and biological process this GO :0034140 and negative regulation of toll-like receptor 3 signaling pathway and biological process this GO :0034144 and negative regulation of toll-like receptor 4 signaling pathway and biological process this GO :0034148 and negative regulation of toll-like receptor 5 signaling pathway and biological process this GO :0035871 and protein K11-linked deubiquitination and biological process this GO :0035872 and nucleotide-binding domain, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0003677 : DNA binding and also this GO :0004221 : ubiquitin thiolesterase activity and also this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0004843 : ubiquitin-specific protease activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity and also this GO :0019900 : kinase binding and also this GO :0043130 : ubiquitin binding and also this GO :0043621 : protein self-association, this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0004843 and ubiquitin-specific protease activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006412 and translation and biological process this GO :0006952 and defense response and biological process this GO :0006954 and inflammatory response and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0009101 and glycoprotein biosynthetic process and biological process this GO :0043124 and negative regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0045071 and negative regulation of viral genome replication and biological process this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0051019 and mitogen-activated protein kinase binding and molecular function this GO :0070373 and negative regulation of ERK1 and ERK2 cascade and biological process this GO :0085032 and modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade and biological process, this GO :0003677 : DNA binding, this GO :0004221 : ubiquitin thiolesterase activity, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004843 : ubiquitin-specific protease activity, this GO :0004843 : ubiquitin-specific protease activity, this GO :0004843 : ubiquitin-specific protease activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0051019 : mitogen-activated protein kinase binding, this GO :0005488 : binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, this GO :0019900 : kinase binding, this GO :0043130 : ubiquitin binding, this GO :0043621 : protein self-association, this GO :0051019 : mitogen-activated protein kinase binding, tumor necrosis factor, TNFAIP3 interacting protein 1 |
| Identity: |
16903 |
| Long gene name: |
TNFAIP3 interacting protein 1 |
| Synonyms: |
NAF1 KIAA0113 ABIN-1 VAN |
| Synonyms name: |
virion-associated nuclear-shuttling protein Nef-associated factor 1 SNP |
| Locus: |
5q33, 1 |
| Discovery year: |
2002-10-03 |
| GenBank acession: |
AJ011895 |
| Entrez gene record: |
10318 |
| Pubmed identfication: |
9923610 11090181 |
| RefSeq identity: |
NM_006058 |
| Havana BLAST/BLAT: |
OTTHUMG00000163722 |