| known also as: |
LXR-a, LXR-b, LXRA, NER, NER-I, NR1H2, RIP15, RLD-1, UNR, alpha, beta (NR1H3, group H, group H, liver X receptor, member 2, member 3, nuclear receptor subfamily 1, nuclear receptor subfamily 1, ubiquitously-expressed nuclear re, Anti-Nuclear Receptor LXR alpha |
| known also as: |
LXR-a, LXR-b, LXRA, NER, NER-I, NR1H2, RIP15, RLD-1, UNR, alpha, beta (NR1H3, group H, group H, liver X receptor, member 2, member 3, nuclear receptor subfamily 1, nuclear receptor subfamily 1, ubiquitously-expressed nuclear re, Nuclear Receptor LXR alpha |
| known also as: |
LXR-a, LXR-b, LXRA, NER, NER-I, NR1H2, RIP15, RLD-1, UNR, alpha, beta (NR1H3, group H, group H, liver X receptor, member 2, member 3, nuclear receptor subfamily 1, nuclear receptor subfamily 1, ubiquitously-expressed nuclear re, Nuclear Receptor LXR alpha |
| known also as: |
beta, Nuclear Receptor LXR alpha |
| known also as: |
LXR-a, LXR-b, LXRA, NER, NER-I, NR1H2, RIP15, RLD-1, UNR, alpha, beta (NR1H3, group H, group H, liver X receptor, member 2, member 3, nuclear receptor subfamily 1, nuclear receptor subfamily 1, ubiquitously-expressed nuclear re, Anti -Nuclear Receptor LXR alpha |
| Other names: |
NAD-dependent deacetylase sirtuin-1, NAD-dependent protein deacetylase sirtuin-1, NAD-dependent protein deacetylase sirtuin-1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, SIR2-like protein 1, SIR2alpha, hSIR2, hSIRT1, regulatory protein SIR2 homolog 1, sir2-like 1, sirtuin 1, sirtuin type 1, NAD-dependent protein deacetylase sirtuin-1 |
| Other gene names: |
75SirT1, SIR2L1, SIR2L1, SIRT1, hSIR2, hSIRT1, SIRT1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Goat |
| Species reactivity: |
Mouse, Rat, Human |
| Specificity and cross-reactivity: |
Species Crossreactivity: human, mouse, rat, This antibody is expected to recognize an epitope corresponding to aa 429-442 of human LXR alpha protein (NP_005684) and to aa 443-456 of human LXR beta protein (NP_009052) |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
0, 0, pH 7, 02% sodium azide, 2, 5% BSA, Supplied as a liquid in Tris saline |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot and For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB), ELISA (EL/EIA) |
| Description: |
2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
LXR-a, LXR-b, LXRA, NER, NER-I, NR1H2, RIP15, RLD-1, UNR, alpha, beta (NR1H3, group H, group H, liver X receptor, member 2, member 3, receptor subfamily 1, receptor subfamily 1, ubiquitously-expressed re, Receptor LXR alpha |
| Short name: |
LXR-a, LXR-b, LXRA, NER, NER-I, NR1H2, RIP15, RLD-1, UNR, alpha, beta (NR1H3, group H, group H, liver X receptor, member 2, member 3, receptor subfamily 1, receptor subfamily 1, ubiquitously-expressed re Antibody, Nuclear Receptor LXR alpha |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
LXR-a, LXR-b, LXRA, NER, NER-I, RIP15, RLD-1, UNR, a, b (nuclear receptor subfamily 1, family H, family H, family H, family H, liver X receptor, member 2, member 2, member 3, member 3, nuclear receptor subfamily 1, nuclear receptor subfamily 1, nuclear receptor subfamily 1, ubiquitously-expressed nuclear re (Antibody to), Nuclear Receptor LXR a |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ATPase binding, BT, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0010467 and gene expression and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010867 and positive regulation of triglyceride biosynthetic process and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0010887 and negative regulation of cholesterol storage and biological process this GO :0030522 and intracellular receptor signaling pathway and biological process this GO :0032270 and positive regulation of cellular protein metabolic process and biological process this GO :0032369 and negative regulation of lipid transport and biological process this GO :0032376 and positive regulation of cholesterol transport and biological process this GO :0034191 and apolipoprotein A-I receptor binding and molecular function this GO :0043401 and steroid hormone mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044255 and cellular lipid metabolic process and biological process this GO :0045723 and positive regulation of fatty acid biosynthetic process and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0010467 and gene expression and biological process this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010867 and positive regulation of triglyceride biosynthetic process and biological process this GO :0010870 and positive regulation of receptor biosynthetic process and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0010887 and negative regulation of cholesterol storage and biological process this GO :0015485 and cholesterol binding and molecular function this GO :0030522 and intracellular receptor signaling pathway and biological process this GO :0032270 and positive regulation of cellular protein metabolic process and biological process this GO :0032369 and negative regulation of lipid transport and biological process this GO :0032376 and positive regulation of cholesterol transport and biological process this GO :0032570 and response to progesterone and biological process this GO :0032810 and sterol response element binding and molecular function this GO :0034145 and positive regulation of toll-like receptor 4 signaling pathway and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0042752 and regulation of circadian rhythm and biological process this GO :0043031 and negative regulation of macrophage activation and biological process this GO :0043277 and apoptotic cell clearance and biological process this GO :0043401 and steroid hormone mediated signaling pathway and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0044255 and cellular lipid metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045723 and positive regulation of fatty acid biosynthetic process and biological process this GO :0045861 and negative regulation of proteolysis and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046965 and retinoid X receptor binding and molecular function this GO :0048384 and retinoic acid receptor signaling pathway and biological process this GO :0048550 and negative regulation of pinocytosis and biological process this GO :0051006 and positive regulation of lipoprotein lipase activity and biological process this GO :0051117 and ATPase binding and molecular function this GO :0060336 and negative regulation of interferon-gamma-mediated signaling pathway and biological process this GO :2000188 and regulation of cholesterol homeostasis and biological process, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048550 and negative regulation of pinocytosis and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0051006 and positive regulation of lipoprotein lipase activity and biological process this GO :0055088 and lipid homeostasis and biological process this GO :0055092 and sterol homeostasis and biological process this GO :0060336 and negative regulation of interferon-gamma-mediated signaling pathway and biological process this GO :0070328 and triglyceride homeostasis and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0090188 and negative regulation of pancreatic juice secretion and biological process this GO :0090341 and negative regulation of secretion of lysosomal enzymes and biological process this GO :2000188 and regulation of cholesterol homeostasis and biological process this GO :2000189 and positive regulation of cholesterol homeostasis and biological process, LXR-a and LXRA and RLD-1, LXR-b and LXRB and NER and NER-I and RIP15 and UNR, NR1H2 and IDBG-64316 and ENSG00000131408 and 7376, NR1H3 and IDBG-42877 and ENSG00000025434 and 10062, NR1H3 and IDBG-637355 and ENSBTAG00000010681 and 507176, Nr1h2 and IDBG-179265 and ENSMUSG00000060601 and 22260, Nr1h3 and IDBG-190792 and ENSMUSG00000002108 and 22259, group H, group H, member 2, member 3, nuclear receptor subfamily 1, nuclei, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003707 and steroid hormone receptor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0004879 and ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0006351 and transcription, this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001133 and sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003707 and steroid hormone receptor activity and molecular function this GO :0004879 and ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001133 : sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003707 : steroid hormone receptor activity and also this GO :0004879 : ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0034191 : apolipoprotein A-I receptor binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046965 : retinoid X receptor binding and also this GO :0051117 : ATPase binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003707 : steroid hormone receptor activity and also this GO :0003713 : transcription coactivator activity and also this GO :0004879 : ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0015485 : cholesterol binding and also this GO :0032810 : sterol response element binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001133 : sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003707 : steroid hormone receptor activity, this GO :0003707 : steroid hormone receptor activity, this GO :0003713 : transcription coactivator activity, this GO :0004879 : ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0004879 : ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0008270 : zinc ion binding, this GO :0015485 : cholesterol binding, this GO :0032810 : sterol response element binding, this GO :0034191 : apolipoprotein A-I receptor binding, this GO :0043565 : sequence-specific DNA binding, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046965 : retinoid X receptor binding, this GO :0051117 : ATPase binding, transcription regulatory region DNA binding, 44371 and IDBG-641008 and ENSBTAG00000003264 and 509622, nuclear receptor subfamily 1 |
| Identity: |
7965 |
| Gene: |
NR1H2 |
More about : NR1H2 |
| Long gene name: |
nuclear receptor subfamily 1 group H member 2 |
| Synonyms gene: |
UNR |
| Synonyms gene name: |
group H, member 2 , ubiquitously-expressed nuclear receptor nuclear receptor subfamily 1 |
| Synonyms: |
NER NER-I RIP15 LXR-b |
| Synonyms name: |
liver X receptor-beta |
| Locus: |
19q13, 3 |
| Discovery year: |
1994-09-19 |
| GenBank acession: |
U14534 |
| Entrez gene record: |
7376 |
| Pubmed identfication: |
7782080 7971966 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000183036 |