| known also as: |
AT Complementation Group A, ATA, ATC, ATD, ATE), ATR Substrate, phosphorylated (Ser/Thr) (Ataxia Telangiectasia Mutated, Anti-ATM |
| known also as: |
AT Complementation Group A, ATA, ATC, ATD, ATE), ATR Substrate, phosphorylated (Ser/Thr) (Ataxia Telangiectasia Mutated, ATM |
| known also as: |
AT Complementation Group A, ATA, ATC, ATD, ATE), ATR SubstRattus norvegicuse, phosphorylated (Ser/Thr) (Ataxia Telangiectasia Mutated, ATM |
| known also as: |
ATR Substrate, ATM |
| known also as: |
AT Complementation Group A, ATA, ATC, ATD, ATE), ATR Substrate, phosphorylated (Ser/Thr) (Ataxia Telangiectasia Mutated, Anti -ATM |
| Other names: |
A-T mutated, AT mutated, Ataxia telangiectasia mutated, OTTHUMP00000232981, Serine-protein kinase ATM, TEL1, ataxia telangiectasia mutated, homolog, serine-protein kinase ATM, telomere maintenance 1, ATM |
| Other gene names: |
AT1, ATA, ATC, ATD, ATDC, ATE, ATM, DKFZp781A0353, MGC74674, N/A, TEL1, TELO1, ATM |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Specificity and cross-reactivity: |
Does not crossreact with corresponding non-phosphorylated sequences or with other phospho-Ser/Thr-containing motifs, Preferentially binds peptides/proteins that contain phospho-Ser/Thr preceded by Leu or similar hydrophobic amino acids at the -1 position and followed by Gln at the +1 position, Species Crossreactivity: All species, Recognizes endogenous levels of proteins containing the ATM/ATR substrate motif |
| Purification method: |
Affinity Purified by Protein A and peptide affinity chromatography |
| Form/Appearance: |
0, 150mM sodium chloride, 50% glycerol, pH 7, 1mg/ml BSA, 5, Supplied as a liquid in 10mM sodium HEPES |
| Storage and shipping: |
Aliquot to avoid repeated freezing and thawing, Aliquots are stable for at least 12 months, For maximum recovery of product, For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, &, Store at 4 degrees Celsius for short term storage, nbsp |
| Tested for:: |
Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB), ELISA (EL/EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
AT Complementation Group A, ATA, ATC, ATD, ATE), ATR Substrate, phosphorylated (Ser/Thr) (Ataxia Telangiectasia Mutated, ATM |
| Short name: |
AT Complementation Group A, ATA, ATC, ATD, ATE) Antibody, ATR Substrate, phosphorylated (Ser/Thr) (Ataxia Telangiectasia Mutated, ATM |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
AT Complementation family A, ATA, ATC, ATD, ATE) (Antibody to), ataxia telangiectasia and Rad3 related Substrate, phosphorylated (L-serine/L-threonine) (Ataxia Telangiectasia Mutated, ataxia telangiectasia mutated |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AT1 and ATA and ATC and ATD and ATDC and ATE and TEL1 and TELO1, ATM and IDBG-629882 and ENSBTAG00000003111 and 526824, ATM and IDBG-70193 and ENSG00000149311 and 472, ATR and IDBG-59521 and ENSG00000175054 and 545, ATR and IDBG-638174 and ENSBTAG00000011529 and 504869, Atm and IDBG-165511 and ENSMUSG00000034218 and 11920, Atr and IDBG-191646 and ENSMUSG00000032409 and 245000, FCTCS and FRP1 and MEC1 and SCKL and SCKL1, alcohol group as acceptor, alcohol group as acceptor, alcohol group as acceptor and also this GO :0032403 : protein complex binding and also this GO :0035174 : histone serine kinase activity and also this GO :0046983 : protein dimerization activity and also this GO :0047485 : protein N-terminus binding, alcohol group as acceptor and also this GO :0032405 : MutLalpha complex binding and also this GO :0032407 : MutSalpha complex binding, alcohol group as acceptor and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0030889 and negative regulation of B cell proliferation and biological process this GO :0032403 and protein complex binding and molecular function this GO :0035174 and histone serine kinase activity and molecular function this GO :0035404 and histone-serine phosphorylation and biological process this GO :0036092 and phosphatidylinositol-3-phosphate biosynthetic process and biological process this GO :0042159 and lipoprotein catabolic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043517 and positive regulation of DNA damage response, alcohol group as acceptor and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0032405 and MutLalpha complex binding and molecular function this GO :0032407 and MutSalpha complex binding and molecular function this GO :0034644 and cellular response to UV and biological process this GO :0042493 and response to drug and biological process this GO :0043393 and regulation of protein binding and biological process this GO :0043517 and positive regulation of DNA damage response, ataxia telangiectasia mutated, nuclei, nuclei, signal transduction by p53 class mediator and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0047485 and protein N-terminus binding and molecular function this GO :0048599 and oocyte development and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0071044 and histone mRNA catabolic process and biological process this GO :0071480 and cellular response to gamma radiation and biological process this GO :0072434 and signal transduction involved in mitotic G2 DNA damage checkpoint and biological process this GO :0090399 and replicative senescence and biological process, signal transduction by p53 class mediator and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0071480 and cellular response to gamma radiation and biological process this GO :0090399 and replicative senescence and biological process, signal transduction by p53 class mediator resulting in cell cycle arrest and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007094 and mitotic spindle assembly checkpoint and biological process this GO :0007131 and reciprocal meiotic recombination and biological process this GO :0007165 and signal transduction and biological process this GO :0007292 and female gamete generation and biological process this GO :0007420 and brain development and biological process this GO :0007507 and heart development and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0010212 and response to ionizing radiation and biological process this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016303 and 1-phosphatidylinositol-3-kinase activity and molecular function this GO :0016572 and histone phosphorylation and biological process this GO :0016772 and transferase activity, telomeric region and cellular component this GO :0001666 and response to hypoxia and biological process this GO :0001756 and somitogenesis and biological process this GO :0002331 and pre-B cell allelic exclusion and biological process this GO :0003677 and DNA binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004677 and DNA-dependent protein kinase activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005819 and spindle and cellular component this GO :0006281 and DNA repair and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006975 and DNA damage induced protein phosphorylation and biological process this GO :0006977 and DNA damage response, this GO :0000077 and DNA damage checkpoint and biological process this GO :0000723 and telomere maintenance and biological process this GO :0000724 and double-strand break repair via homolo this GO us recombination and biological process this GO :0000781 and chromosome, this GO :0000077 and DNA damage checkpoint and biological process this GO :0001741 and XY body and cellular component this GO :0003677 and DNA binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005654 and nucleoplasm and cellular component this GO :0005694 and chromosome and cellular component this GO :0006260 and DNA replication and biological process this GO :0006281 and DNA repair and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007049 and cell cycle and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008152 and metabolic process and biological process this GO :0008156 and negative regulation of DNA replication and biological process this GO :0016605 and PML body and cellular component this GO :0016772 and transferase activity, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004677 : DNA-dependent protein kinase activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016303 : 1-phosphatidylinositol-3-kinase activity and also this GO :0016772 : transferase activity, this GO :0003677 : DNA binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004677 : DNA-dependent protein kinase activity, this GO :0005488 : binding, this GO :0005488 : binding, this GO :0005515 : protein binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005524 : ATP binding, this GO :0016303 : 1-phosphatidylinositol-3-kinase activity, this GO :0016772 : transferase activity, this GO :0016772 : transferase activity, this GO :0016773 : phosphotransferase activity, this GO :0016773 : phosphotransferase activity, this GO :0032403 : protein complex binding, this GO :0032405 : MutLalpha complex binding, this GO :0032407 : MutSalpha complex binding, this GO :0035174 : histone serine kinase activity, this GO :0046983 : protein dimerization activity, this GO :0047485 : protein N-terminus binding, transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0016773 : phosphotransferase activity, transferring phosphorus-containing groups and also this GO :0016773 : phosphotransferase activity, transferring phosphorus-containing groups and molecular function this GO :0016773 and phosphotransferase activity, transferring phosphorus-containing groups and molecular function this GO :0016773 and phosphotransferase activity, ataxia telangiectasia and Rad3 related |
| Identity: |
780 |
| Gene: |
ATD |
More about : ATD |
| Long gene name: |
asphixiating thoracic dystrophy (chondroectodermal dysplasia-like syndrome) |
| Locus: |
12p12, 2-p11, 21 |
| Discovery year: |
1995-12-19 |
| Pubmed identfication: |
7702088 |