| Also known as: |
Insulin-like Growth Factor-1 |
| Other names: |
IGF-IA, IGF-IB, Insulin-like growth factor I, MGF, Somatomedin, insulin-like growth factor 1 (somatomedin C), insulin-like growth factor I, insulin-like growth factor IA, insulin-like growth factor IB, mechano growth factor, somatomedin-C, insulin-like growth factor I isoform 4 preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
IGF1 |
| Other gene names: |
IGF-I, IGF-I, IGF1A, IGFI, Igf-1, Igf1, IGF1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG1 |
| Clone: |
M23 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing, IGF-1 stimulates the proliferation of a wide range of cell types including muscle, Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA, It functions as an autocrine regulator of growth, MSF, Proinsulin, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, and Insulin, bone and cartilage tissue, thyroid and colon, This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11 |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Description: |
IGF-1 acts via specific receptor, IGF-1R, IGF-II, Insulin-like growth factor -1 shares structural homology with proinsulin and is mainly produced by liver, Raf/Ras and PI3K cascades, a heterodimeric tyrosine kinase receptor that signals to various second messenger pathways such as MAPK, insulin-like growth factors -1 and -2 are important regulators of signaling that mediates growth and metabolism in cells, IGF-I |
| Gene target: |
Insulin-like Growth Factor-1 1) |
| Short name: |
Insulin-like Growth Factor-1 (IGF-1) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, igfs, Antibody |
| Alternative name: |
Insulin-like Growth Factor-1 (IGF-1) (Antibody to) |
| Alternative technique: |
antibodies |