| Also known as: |
CD44 |
| Other names: |
CD44 antigen, CD44 antigen, CD44 molecule (Indian blood group), CD_antigen: CD44, CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hermes antigen, Hyaluronate receptor, PGP-1, PGP-I, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, cell surface glycoprotein CD44, chondroitin sulfate proteoglycan 8, epican, extracellular matrix receptor III, hematopoietic cell E- and L-selectin ligand, heparan sulfate proteoglycan, homing function and Indian blood group system, hyaluronate receptor, phagocytic glycoprotein 1, CD44 antigen isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD44 |
| Other gene names: |
CD44, CDW44, CSPG8, ECMR-III, ECMR-III, HCELL, HUTCH-I, IN, LHR, LHR, MC56, MDU2, MDU2, MDU3, MDU3, MIC4, MIC4, PGP-1, PGP-I, Pgp1, CD44 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG2a |
| Clone: |
156-3C11 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Baboon, Due to limited knowledge and inability for testing each and every species, Green Monkey, Others-not tested, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium, Higher molecular weight isoforms are described in epithelial cells (CD44v), Its epitope is resistant to digestion by trypsin and chymotrypsin, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The CD44 family of glycoproteins exists in a number of variant isoforms, This particular antibody might cross react with speacies outside of the listed ones, and granulocytes (Leucocyte Typing Workshop V), monocytes, the most common being the standard 85-95kDa or hematopoietic variant (CD44s), which are believed to function in intercellular adhesion and stromal binding, Recognizes a cell surface glycoprotein of 80-95kDa (CD44) on lymphocytes |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
CD44/ HCAM Std |
| Short name: |
Antibody, CD44/ HCAM Std |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
(Antibody to), CD44 molecule (Indian blood group)/ HCAM Std |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD44 and IDBG-39556 and ENSG00000026508 and 960, CD44 and IDBG-636564 and ENSBTAG00000011578 and 281057, CDW44 and CSPG8 and ECMR-III and HCELL and HUTCH-I and IN and LHR and MC56 and MDU2 and MDU3 and MIC4 and Pgp1, Cd44 and IDBG-193505 and ENSMUSG00000005087 and 12505, Cell surfaces, hyaluronic acid binding, signal transduction by p53 class mediator and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044344 and cellular response to fibroblast growth factor stimulus and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050900 and leukocyte migration and biological process this GO :0051216 and cartilage development and biological process this GO :0060333 and interferon-gamma-mediated signaling pathway and biological process this GO :0060442 and branching involved in prostate gland morphogenesis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070487 and monocyte aggregation and biological process this GO :1900625 and positive regulation of monocyte aggregation and biological process this GO :1902166 and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process, this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0002246 and wound healing involved in inflammatory response and biological process this GO :0004415 and hyalurononglucosaminidase activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005540 and hyaluronic acid binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010628 and positive regulation of gene expression and biological process this GO :0016020 and membrane and cellular component this GO :0016055 and Wnt signaling pathway and biological process this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030203 and glycosaminoglycan metabolic process and biological process this GO :0030212 and hyaluronan metabolic process and biological process this GO :0030214 and hyaluronan catabolic process and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0034116 and positive regulation of heterotypic cell-cell adhesion and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043518 and negative regulation of DNA damage response, this GO :0004415 : hyalurononglucosaminidase activity, this GO :0004415 : hyalurononglucosaminidase activity and also this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding and also this GO :0005518 : collagen binding and also this GO :0005540 : hyaluronic acid binding, this GO :0004888 : transmembrane signaling receptor activity, this GO :0005515 : protein binding, this GO :0005518 : collagen binding, this GO :0005540 : hyaluronic acid binding, CD44 molecule (Indian blood group) |
| Identity: |
1681 |
| Gene: |
CD44 |
More about : CD44 |
| Long gene name: |
CD44 molecule (Indian blood group) |
| Synonyms gene: |
MIC4 MDU2 MDU3 |
| Synonyms gene name: |
CD44 antigen (homing function and Indian blood group system) |
| Synonyms: |
IN MC56 Pgp1 CD44R HCELL CSPG8 |
| Synonyms name: |
hematopoietic cell E- and L-selectin ligand chondroitin sulfate proteoglycan 8 |
| Locus: |
11p13 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
M59040 |
| Entrez gene record: |
960 |
| Pubmed identfication: |
2454887 |
| RefSeq identity: |
NM_000610 |
| Classification: |
Proteoglycans CD molecules Blood group antigens |
| Havana BLAST/BLAT: |
OTTHUMG00000044388 |
| Locus Specific Databases: |
LRG_815 |