MUC18/ CD146

Catalog number:	GENTAUR-58be2342ee535 Buy Now
Price:	282 €
Supplier:	acr
Product name:	MUC18/ CD146
Quantity:	20 Вµg
Related search:	muc cell melanoma gene antibody molecule species domain synonyms need

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Also known as:	MUC18
Other names:	CD_antigen: CD146, Cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, Gicerin, Melanoma cell adhesion molecule, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, S-endo 1 endothelial-associated antigen, S-endo 1 endothelial-associated antigen, cell surface glycoprotein MUC18, cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion molecule, melanoma-associated antigen A32, melanoma-associated antigen MUC18, N/A
Category:	Antibodies
Subcategory:	Mnoclonal antibodies
Gene name:	MCAM
Other gene names:	CD146, MCAM, MUC18, MUC18, MCAM
Clonality:	Monoclonal
Immunoglobulin isotype:	kappa, IgG1
Clone:	OJ79c
Host organism:	Mouse (Mus musculus)
Species reactivity:	Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity:	MUC 18 or CD146, Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, also designated MCAM, but not normal melanocytes, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule, The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein
Storage and shipping:	Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications::	Flow Cytometry (0, Immunofluorescence (0, Immunohistology (Frozen) (0, Immunoprecipitation (1-2ug/500ug protein), Western Blot (0, order antibody without BSA), 0ug/ml for 30 min at RT Opt, 0ug/ml), 0ug/ml), 5-1, 5-1, 5-1, 5-1ug/million cells), ELISA (For coating
Gene target:	MUC18/ CD146
Short name:	MUC18/ CD146
Alternative name:	MUC18/ CD146
Identity:	6934
Gene:	MCAM | More about : MCAM
Long gene name:	melanoma cell adhesion molecule
Synonyms:	MUC18 CD146
Synonyms name:	Gicerin
Locus:	11q23, 3
Discovery year:	1995-12-18
GenBank acession:	X68264
Entrez gene record:	4162
Pubmed identfication:	2602381 10702685
Classification:	C2-set domain containing CD molecules V-set domain containing Immunoglobulin like domain containing
Havana BLAST/BLAT:	OTTHUMG00000166197

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