| Also known as: |
Actin |
| Other names: |
Actin, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, actin, actin, alpha 2, alpha-cardiac actin, aorta, aortic smooth muscle, aortic smooth muscle, aortic smooth muscle, cell growth-inhibiting gene 46 protein, smooth muscle, actin |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
ACTA2 |
| Other gene names: |
AAT6, ACTA2, ACTSA, ACTSA, ACTVS, MYMY5, ACTA2 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG2a |
| Clone: |
SPM332 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Baboon, Cat, Chicken, Cow, Dog, Due to limited knowledge and inability for testing each and every species, Goat, Guinea pig, Monkey, Mouse (Mus musculus), Pig, Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), Sheep, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
In most cases of rhabdomyosarcoma, Its epitope lies in the first four N-terminal amino acids, Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This MAb does not stain cardiac or skeletal muscle, This MAb is highly specific to actin from smooth muscles, This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors, This particular antibody might cross react with speacies outside of the listed ones, however, it does stain myofibroblasts and myoepithelial cells, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive, Actin is a major component of the cytoskeleton and is present in most cell types |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA) |
| Gene target: |
Smooth Muscle, Actin |
| Short name: |
Smooth Muscle, Actin |
| Alternative name: |
Smooth Muscle, Actin |