| Specificity and cross-reactivity: |
CA19-9 can predict recurrence of disease prior to radiographic or clinical findings, In normal tissues, Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This MAb is superb for staining of formalin-fixed, This particular antibody might cross react with speacies outside of the listed ones, When used serially, a carbohydrate epitope expressed on a high MW (>, and pancreas, and sweat glands, including adenocarcinomas of the stomach, intestine, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens, kidney, paraffin-embedded tissues, salivary gland, sialyl Lewisa antigen is present in ductal epithelium of the breast, 400kDa) mucin glycoprotein, CA19-9 |