| Also known as: |
HCC-4 |
| Other names: |
C-C motif chemokine 16, C-C motif chemokine 16, Chemokine CC-4, Chemokine LEC, HCC-4, IL-10-inducible chemokine, IL-10-inducible chemokine, LCC-1, LMC, Liver-expressed chemokine, Lymphocyte and monocyte chemoattractant, MTN-1, Monotactin-1, NCC-4, Small-inducible cytokine A16, chemokine (C-C motif) ligand 16, chemokine CC-4, chemokine LEC, liver CC chemokine-1, liver-expressed chemokine, lymphocyte and monocyte chemoattractant, member 16, monotactin-1, new CC chemokine 4, small inducible cytokine subfamily A (Cys-Cys), small-inducible cytokine A16, C-C motif chemokine 16 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CCL16 |
| Other gene names: |
CCL16, CKb12, HCC-4, HCC-4, ILINCK, ILINCK, LCC-1, LEC, LMC, LMC, MTN-1, Mtn-1, NCC-4, NCC4, NCC4, SCYA16, SCYA16, SCYL4, CCL16 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG1 |
| Clone: |
LEC66 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Also shows potent myelo-suppressive activity, Highly expressed in LPS- and IFN-gamma-activated monocytes, Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES, Mainly expressed in liver, Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The ability of HCC-4 to markedly improve recognition of poorly immunogenic cells suggests that it could be an effective component of antitumor vaccines, This particular antibody might cross react with speacies outside of the listed ones, also found in spleen and thymus, and some T-cell clones, but not for resting lymphocytes and neutrophils, gamma-delta T-cells, including natural killer cells, suppresses proliferation of myeloid progenitor cells, weakly in some lymphocytes, Shows chemotactic activity for lymphocytes and monocytes but not neutrophils |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Functional Studies, ELISA (EIA) |
| Gene target: |
HCC-4 |
| Short name: |
HCC-4 |
| Alternative name: |
HCC-4 |
| Identity: |
9907 |
| Gene: |
RBMS1 |
More about : RBMS1 |
| Long gene name: |
RNA binding motif single stranded interacting protein 1 |
| Synonyms gene: |
C2orf12 |
| Synonyms gene name: |
chromosome 2 open reading frame 12 |
| Synonyms: |
SCR2 MSSP-1 MSSP-2 MSSP-3 YC1 HCC-4 DKFZp564H0764 |
| Synonyms name: |
suppressor of cdc 2 (cdc13) with RNA binding motif 2 c-myc gene single strand binding protein 2 |
| Locus: |
2q24, 2 |
| Discovery year: |
1998-02-27 |
| GenBank acession: |
D28482 |
| Entrez gene record: |
5937 |
| Pubmed identfication: |
8041632 8134115 7838710 |
| RefSeq identity: |
NM_016836 |
| Classification: |
RNA binding motif containing |
| Havana BLAST/BLAT: |
OTTHUMG00000132031 |