| Also known as: |
PAX7 |
| Other names: |
HuP1, PAX7 transcriptional factor, Paired box protein Pax-7, paired box 7, paired box homeotic gene 7, paired box protein Pax-7, paired domain gene 7, paired box protein Pax-7 isoform 3 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PAX7 |
| Other gene names: |
HUP1, HUP1, PAX7, PAX7B, RMS2, PAX7 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG1 |
| Clone: |
PAX7/497 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Rat (Rattus norvegicus) Chicken, Zebrafish, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveo- lar rhabdomyosarcoma), In addition, In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle, Mutations in the Pax family of proteins have been linked to disease and cancer in humans, Pax-7 is a protein specifically expressed in cultured satellite cell- derived myoblasts, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, the family is involved in a variety of signal transduction pathways in the adult organism, The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), ELISA (EIA) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
PAX7 |
| Short name: |
PAX7 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
paired box 7 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007519 and skeletal muscle tissue development and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0010453 and regulation of cell fate commitment and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0014813 and satellite cell commitment and biological process this GO :0021527 and spinal cord association neuron differentiation and biological process this GO :0021904 and dorsal/ventral neural tube patterning and biological process this GO :0031062 and positive regulation of histone methylation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043393 and regulation of protein binding and biological process this GO :0043403 and skeletal muscle tissue regeneration and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048663 and neuron fate commitment and biological process this GO :0048706 and embryonic skeletal system development and biological process this GO :0051216 and cartilage development and biological process this GO :0060415 and muscle tissue morphogenesis and biological process this GO :2000288 and positive regulation of myoblast proliferation and biological process, HUP1 and PAX7B and RMS2, PAX7 and IDBG-645775 and ENSBTAG00000014967 and 536229, PAX7 and IDBG-92024 and ENSG00000009709 and 5081, Pax7 and IDBG-201015 and ENSMUSG00000028736 and 18509, nuclei, sequence-specific DNA binding, this GO :0000983 and RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006338 and chromatin remodeling and biological process this GO :0006355 and regulation of transcription, this GO :0000983 : RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, this GO :0000983 : RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, paired box 7 |
| Identity: |
8621 |
| Gene: |
PAX7 |
More about : PAX7 |
| Long gene name: |
paired box 7 |
| Synonyms gene name: |
paired box gene 7 |
| Synonyms: |
Hup1 |
| Locus: |
1p36, 13 |
| Discovery year: |
1992-11-20 |
| GenBank acession: |
X96743 |
| Entrez gene record: |
5081 |
| Pubmed identfication: |
7981748 8431641 |
| RefSeq identity: |
NM_002584 |
| Classification: |
PRD class homeoboxes and pseudogenes Paired boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000002433 |