| Also known as: |
Ep-CAM |
| Other names: |
Adenocarcinoma-associated antigen, CD_antigen: CD326, Cell surface glycoprotein Trop-1, EGP, EGP314, Epithelial cell adhesion molecule, Epithelial cell surface antigen, Epithelial glycoprotein, Epithelial glycoprotein 314, KS 1/4 antigen, KSA, Major gastrointestinal tumor-associated protein GA733-2, Tumor-associated calcium signal transducer 1, adenocarcinoma-associated antigen, cell surface glycoprotein Trop-1, chromosome 4, epithelial cell adhesion molecule, epithelial cell adhesion molecule, epithelial glycoprotein 314, hEGP314, human epithelial glycoprotein-2, major gastrointestinal tumor-associated protein GA733-2, membrane component, surface marker (35kD glycoprotein), tumor-associated calcium signal transducer 1, epithelial cell adhesion molecule |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
TACSTD1 |
| Other gene names: |
DIAR5, EGP, EGP-2, EGP314, EGP314, EGP40, EPCAM, ESA, Ep-CAM, GA733-2, HNPCC8, KS1/4, KSA, M1S2, M4S1, M4S1, MIC18, MIC18, MK-1, TACSTD1, TACSTD1, TROP1, TROP1, hEGP314, EPCAM |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG1 |
| Clone: |
MOC-31 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Does not react with Rat (Rattus norvegicus), Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma, This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma, This particular antibody might cross react with speacies outside of the listed ones, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM), Binding epitope of this antibody is located in the first EGF-like repeat domain (EGF1) between amino acids 27-59 of Ep-CAM |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS) |
| Gene target: |
Ep-CAM/ CD326 |
| Short name: |
Ep-CAM/ CD326 |
| Alternative name: |
Ep-CAM/ CD326 |
| Identity: |
11529 |
| Gene: |
EPCAM |
More about : EPCAM |
| Long gene name: |
epithelial cell adhesion molecule |
| Synonyms gene: |
M4S1 MIC18 TACSTD1 |
| Synonyms gene name: |
antigen identified by monoclonal antibody AUA1 tumor-associated calcium signal transducer 1 |
| Synonyms: |
Ly74 TROP1 GA733-2 EGP34 EGP40 EGP-2 KSA CD326 Ep-CAM HEA125 KS1/4 MK-1 MH99 MOC31 323/A3 17-1A TACST-1 CO-17A ESA |
| Locus: |
2p21 |
| Discovery year: |
1995-10-02 |
| GenBank acession: |
M33011 |
| Entrez gene record: |
4072 |
| Pubmed identfication: |
8382772 11306819 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000128853 |
| Locus Specific Databases: |
Colon cancer gene variant databases LRG_215 |