| Also known as: |
Carcinoembryonic Antigen |
| Other names: |
CD_antigen: CD66e, CEA, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, Meconium antigen 100, carcinoembryonic antigen-related cell adhesion molecule 5, carcinoembryonic antigen-related cell adhesion molecule 5, meconium antigen 100, carcinoembryonic antigen-related cell adhesion molecule 5 preproprotein |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CEACAM5 |
| Other gene names: |
CD66e, CEA, CEA, CEA, CEACAM5, CEACAM5 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
C66/261), IgG2a (COL-1) + IgG1 (CEA31 & |
| Clone: |
COL-1 + CEA31 + C66/261 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Anti-CEA positivity is seen in adenocarcinomas from the lung, Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+), CEA is not found in benign glands, CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors, It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This MAb reacts with nonspecific cross-reacting antigen (NCA) and shows a cross-reaction with human polymorphonuclear leucocytes, This particular antibody might cross react with speacies outside of the listed ones, and endocervix, colon, esophagus, gallbadder, identified as different members of CEA family, or malignant prostatic cells, ovary, pancreas, salivary gland, stomach, stroma, urachus, This antibody recognizes proteins of 80-200kDa |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS) |
| Gene target: |
Carcinoembryonic (CEA)/ CD66 |
| Short name: |
Carcinoembryonic Antigen (CEA)/ CD66 |
| Alternative name: |
Carcinoembryonic protein (CEA)/ CD66 |
| Identity: |
1817 |
| Gene: |
CEACAM5 |
More about : CEACAM5 |
| Long gene name: |
carcinoembryonic antigen related cell adhesion molecule 5 |
| Synonyms gene: |
CEA |
| Synonyms gene name: |
carcinoembryonic antigen-related cell adhesion molecule 5 |
| Synonyms: |
CD66e |
| Locus: |
19q13, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M17303 |
| Entrez gene record: |
1048 |
| RefSeq identity: |
NM_004363 |
| Classification: |
I-set domain containing Immunoglobulin like domain containing CD molecules V-set domain containing Carcinoembryonic antigen related cell adhesion molecule family |
| Havana BLAST/BLAT: |
OTTHUMG00000151061 |