| Also known as: |
Mitochondria |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
kappa, IgG1 |
| Clone: |
113-1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Does not react with Mouse (Mus musculus) and Rat (Rattus norvegicus), Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Abundant granular eosinophilic cytoplasm is a common feature of renal oncocytoma, However, Immunostaining pattern with anti-mitochondrial MAb 113-1 has been reported as a useful discriminatory adjunct in the complex differential diagnosis of granular renal cell tumors, It can be used to stain mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions, It produces a spaghetti-like pattern in normal and malignant cells, It reacts specifically with human cells, Moreover, One study highlights the usefulness of 113-1 MAb to facilitate the classification of salivary tumors, Salivary gland tumors usually show great variability both in their morphopathology as well as their clinical behavior, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The chief reason for their distinction from one another is the difference in their biologic behavior, This antibody is an excellent marker for human cells in xenographic model research, This particular antibody might cross react with speacies outside of the listed ones, an aspect that may sometimes have not only diagnostic implications, and the granular variant of clear cell renal cell carcinoma (RCC), but also prognostic, chromophobe renal cell carcinoma, eosinophilic variant of papillary renal cell carcinoma, including neurons and embryonic stem cells, precise characterization may be difficult in some cases because of overlapping morphologic features, MAb 113-1 recognizes a 60kDa antigen associated with the mitochondria in human cells |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), Immunofluorescence (IF) |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| Gene target: |
Mitochondria |
| Short name: |
Mitochondria Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Mitochondria (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6466 |
| Gene: |
KSS |
More about : KSS |
| Long gene name: |
Kearns-Sayre syndrome |
| Locus: |
mitochondria |
| Discovery year: |
1990-06-11 |