| Also known as: |
Cytokeratin |
| Other names: |
67 kDa cytokeratin, 67 kDa cytokeratin, CK-1, CK-1, Cytokeratin-1, Hair alpha protein, K1, Keratin, Keratin-1, Type-II keratin Kb1, cytokeratin 1, cytokeratin-1, epidermolytic hyperkeratosis 1, hair alpha protein, keratin, keratin 1, type II cytoskeletal 1, type II cytoskeletal 1, type II cytoskeletal 1, type-II keratin Kb1, keratin |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
KRT1 |
| Gene name synonims: |
KRT4, KRT5, KRT6, KRT8, KRT3 |
| Other gene names: |
CK-1, CK1, EHK, EHK1, EPPK, K1, K1, KRT1, KRT1A, KRTA, NEPPK, KRT1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
AE-3 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Chicken, Cow, Dog, Due to limited knowledge and inability for testing each and every species, Monkey, Mouse (Mus musculus), Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
5, 5, 6, 45, 46, 48, 50, 50', 51, 52kDa (CK8), 55, 56, 56kDa (CK6), 58, 58kDa (CK5), 59, 59kDa (CK4), 64, 64kDa (CK3), AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, MAb AE3 recognizes the 65-67, Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The acidic keratins have molecular weights (MW) of 56, This particular antibody might cross react with speacies outside of the listed ones, Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <, adenocarcinoma of the lung, and 40kDa, and 52kDa keratins of basic subfamily, and esophageal cancer, breast cancer, liver carcinoma, squamous vs, which differentiates epithelial tumors from non-epithelial tumors e, which include 67kDa (CK1), 0) subfamilies, 7) and basic (pI >, This MAb recognizes basic (Type II or HMW) cytokeratins, g |
| Storage and shipping: |
Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistology (IH), Western Blot (WB), ELISA (EIA) |
| Description: |
7 are often produced recombinant and shouldn&rsquo, Basic proteins pH>, t be precipitated by formic acid buffer |
| Gene target: |
II HMW), Cytokeratin |
| Short name: |
( II HMW), Cytokeratin |
| Alternative name: |
Basic (classification II and HMW), Cytokeratin |
| Identity: |
29276 |
| Gene: |
CFAP97 |
More about : CFAP97 |
| Long gene name: |
cilia and flagella associated protein 97 |
| Synonyms gene: |
KIAA1430 |
| Synonyms gene name: |
KIAA1430 |
| Synonyms: |
DKFZp434F1728 hmw |
| Locus: |
4q35, 1 |
| Discovery year: |
2004-04-21 |
| GenBank acession: |
AB037851 |
| Entrez gene record: |
57587 |
| Pubmed identfication: |
10718198 24554765 |
| RefSeq identity: |
XM_087593 |
| Havana BLAST/BLAT: |
OTTHUMG00000160468 |