| known also as: |
EC 2, JAKL, LJAK), Leukocyte Janus Kinase, 2, 7, 10, Anti-JAK3 (Janus Kinase 3 |
| known also as: |
EC 2, JAKL, LJAK), Leukocyte Janus Kinase, 2, 7, 10, JAK3 (Janus Kinase 3 |
| known also as: |
EC 2, JAKL, LJAK), Leukocyte Janus Kinase, 2, 7, 10, JAK3 (Janus Kinase 3 |
| known also as: |
JAK3 |
| known also as: |
EC 2, JAKL, LJAK), Leukocyte Janus Kinase, 2, 7, 10, Anti -JAK3 (Janus Kinase 3 |
| Other names: |
JAK-3, Janus kinase 3, Janus kinase 3, Janus kinase 3 (a protein tyrosine kinase, Leukocyte janus kinase, OTTHUMP00000230594, OTTHUMP00000230595, Tyrosine-protein kinase JAK3, leukocyte Janus kinase, leukocyte), tyrosine-protein kinase JAK3, JAK3_HUMAN |
| Other gene names: |
JAK-3, JAK3, JAK3_HUMAN, JAKL, L-JAK, LJAK, N/A, JAK3 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Mouse, Host: Rabbit |
| Species reactivity: |
Mouse |
| Specificity and cross-reactivity: |
Does not react with human JAK3, Mr 125kD and JAK3 degradation products, Mr 95-120kD, No reaction was noted with immunoprecipitated mouse JAK1 and JAK2, Recognizes mouse JAK3 |
| Purification method: |
Serum |
| Form/Appearance: |
05% sodium azide, Supplied as a liquid (whole antiserum) containing 0 |
| Storage and shipping: |
For maximum recovery of product, Further dilutions can be made in assay buffer, Long-term storage should be done after aliquoting the item and freezing the aliqotes at -20 degrees Celsius, Under these conditions the aliquots will be stable for at least one year if kept at -20 °, centrifuge the original vial after thawing and prior to removing the cap, C, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
EC 2, JAKL, LJAK), Leukocyte Janus Kinase, 2, 7, 10, JAK3 (Janus Kinase 3 |
| Short name: |
EC 2, JAKL, LJAK) Antibody, Leukocyte Janus Kinase, 2, 7, 10, JAK3 (Janus Kinase 3 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
EC 2, JAKL, LJAK) (Antibody to), Leukocyte Janus phosphorylation catalyst, 2, 7, 10, Janus kinase 3 (Janus phosphorylation catalyst 3 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, JAK-3 and JAK3_HUMAN and JAKL and L-JAK and LJAK, JAK3 and IDBG-37201 and ENSG00000105639 and 3718, Jak3 and IDBG-166648 and ENSMUSG00000031805 and 16453, Plasma membranes, this GO :0002731 and negative regulation of dendritic cell cytokine production and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007167 and enzyme linked receptor protein signaling pathway and biological process this GO :0007260 and tyrosine phosphorylation of STAT protein and biological process this GO :0007262 and STAT protein import into nucleus and biological process this GO :0012505 and endomembrane system and cellular component this GO :0016020 and membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019903 : protein phosphatase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019903 : protein phosphatase binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019903 and protein phosphatase binding and molecular function this GO :0030183 and B cell differentiation and biological process this GO :0032693 and negative regulation of interleukin-10 production and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035771 and interleukin-4-mediated signaling pathway and biological process this GO :0043029 and T cell homeostasis and biological process this GO :0045087 and innate immune response and biological process this GO :0045221 and negative regulation of FasL biosynthetic process and biological process this GO :0045626 and negative regulation of T-helper 1 cell differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050868 and negative regulation of T cell activation and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0070232 and regulation of T cell apoptotic process and biological process this GO :0070244 and negative regulation of thymocyte apoptotic process and biological process this GO :0070669 and response to interleukin-2 and biological process this GO :0070670 and response to interleukin-4 and biological process this GO :0070672 and response to interleukin-15 and biological process this GO :0071104 and response to interleukin-9 and biological process this GO :2000670 and positive regulation of dendritic cell apoptotic process and biological process this GO :2001241 and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, 44422 and IDBG-641863 and ENSBTAG00000020904 and 538276, Janus kinase 3 |
| Identity: |
6193 |
| Gene: |
JAK3 |
More about : JAK3 |
| Long gene name: |
Janus kinase 3 |
| Synonyms: |
L-JAK JAKL LJAK JAK3_HUMAN JAK-3 |
| Synonyms name: |
tyrosine-protein kinase JAK3 leukocyte Janus kinase |
| Locus: |
19p13, 11 |
| Discovery year: |
1994-12-19 |
| GenBank acession: |
U31601 |
| Entrez gene record: |
3718 |
| Pubmed identfication: |
8921370 9226382 |
| RefSeq identity: |
NM_000215 |
| Havana BLAST/BLAT: |
OTTHUMG00000165648 |
| Locus Specific Databases: |
JAK3base: Mutation registry for autosomal recessive severe combined JAK3 deficiency LRG_77 |