| known also as: |
NGS-17, NGS17, TAP-associated Protein, TAP-binding Protein, TAPA, TAPBP), TPSN, Anti-Tapasin (TPN |
| known also as: |
NGS-17, NGS17, TAP-associated Protein, TAP-binding Protein, TAPA, TAPBP), TPSN, Tapasin (TPN |
| known also as: |
NGS-17, NGS17, TAP-associated Protein, TAP-binding Protein, TAPA, TAPBP), TPSN, Tapasin (TPN |
| known also as: |
Tapasin |
| known also as: |
NGS-17, NGS17, TAP-associated Protein, TAP-binding Protein, TAPA, TAPBP), TPSN, Anti -Tapasin (TPN |
| Other names: |
NGS-17, NGS-17, OTTHUMP00000029102, OTTHUMP00000178697, OTTHUMP00000178698, OTTHUMP00000178699, TAP binding protein (tapasin), TAP-associated protein, TAP-associated protein, TAP-binding protein, TAP-binding protein, Tapasin, tapasin, tapasin |
| Other gene names: |
NGS17, NGS17, TAPA, TAPA, TAPBP, TPN, TPSN, TAPBP |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Mouse, Rat, Human |
| Specificity and cross-reactivity: |
corresponding to the apparent molecular mass of tapasin on SDS-PAGE immunoblots, in samples from human origin, Detects an ~48kD protein |
| Purification method: |
Affinity Purified by Protein A affinity chromatography |
| Form/Appearance: |
0, 50% glycerol, in PBS, pH 7, 09% azide, 2, Supplied as a liquid |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Freeze productone should be stored at -20 degrees Celsius, Further dilutions can be made in assay buffer, add glycerol (40-50%) and aliquot, centrifuge the original vial after thawing and prior to removing the cap, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Immunoprecipitation (IP), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
NGS-17, NGS17, TAP-associated Protein, TAP-binding Protein, TAPA, TAPBP), TPSN, Tapasin (TPN |
| Short name: |
NGS-17, NGS17, TAP-associated Protein, TAP-binding Protein, TAPA, TAPBP), TPSN, Tapasin (TPN |
| Alternative name: |
NGS-17, NGS17, TAP binding protein (tapasin)), TAP-associated Protein, TAP-binding Protein, TAPA, TPSN, Tapasin (TPN |
| Alternative to gene target: |
NGS17 and TAPA and TPN and TPSN, Plasma membranes, TAP-dependent and biological process this GO :0005515 and protein binding and molecular function this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005789 and endoplasmic reticulum membrane and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006890 and retrograde vesicle-mediated transport, TAPBP and IDBG-304230 and ENSG00000231925 and 6892, TAPBP and IDBG-629016 and ENSBTAG00000016828 and 504335, Tapbp and IDBG-168250 and ENSMUSG00000024308 and 21356, this GO :0000139 and this GO lgi membrane and cellular component this GO :0002397 and MHC class I protein complex assembly and biological process this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0015433 : peptide antigen-transporting ATPase activity and also this GO :0042288 : MHC class I protein binding and also this GO :0042605 : peptide antigen binding and also this GO :0046978 : TAP1 binding and also this GO :0046979 : TAP2 binding and also this GO :0051082 : unfolded protein binding, this GO :0015433 : peptide antigen-transporting ATPase activity, this GO :0042288 : MHC class I protein binding, this GO :0042605 : peptide antigen binding, this GO :0046978 : TAP1 binding, this GO :0046979 : TAP2 binding, this GO :0051082 : unfolded protein binding, this GO lgi to ER and biological process this GO :0006952 and defense response and biological process this GO :0006955 and immune response and biological process this GO :0015433 and peptide antigen-transporting ATPase activity and molecular function this GO :0015833 and peptide transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019885 and antigen processing and presentation of endogenous peptide antigen via MHC class I and biological process this GO :0042288 and MHC class I protein binding and molecular function this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042605 and peptide antigen binding and molecular function this GO :0042824 and MHC class I peptide loading complex and cellular component this GO :0042825 and TAP complex and cellular component this GO :0042886 and amide transport and biological process this GO :0046978 and TAP1 binding and molecular function this GO :0046979 and TAP2 binding and molecular function this GO :0050823 and peptide antigen stabilization and biological process this GO :0051082 and unfolded protein binding and molecular function this GO :0071556 and integral component of lumenal side of endoplasmic reticulum membrane and cellular component, unfolded protein binding, TAP binding protein (tapasin) |
| Identity: |
11566 |
| Gene: |
TAPBP |
More about : TAPBP |
| Long gene name: |
TAP binding protein |
| Synonyms gene name: |
TAP binding protein (tapasin) |
| Synonyms: |
TAPA |
| Synonyms name: |
tapasin |
| Locus: |
6p21, 32 |
| Discovery year: |
1997-12-17 |
| GenBank acession: |
Y13582 |
| Entrez gene record: |
6892 |
| Pubmed identfication: |
9238042 |
| Classification: |
C1-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031090 |
| Locus Specific Databases: |
TAPBPbase: Mutation registry for Tapasin deficiency LRG_114 |