| known also as: |
ACUG, Arthrocutaneouveal Granulomatosis, BLAU, CARD15, CD, Caspase Recruitment Domain 15, IBD1, Inflammatory Bowel Disease Protein 1, LRR Containing Protein, NOD2 Protein, NOD2B, PSORAS1), Anti-Nod2 (Nucleotide Binding Oligomerization Domain 2 |
| known also as: |
ACUG, Arthrocutaneouveal Granulomatosis, BLAU, CARD15, CD, Caspase Recruitment Domain 15, IBD1, Inflammatory Bowel Disease Protein 1, LRR Containing Protein, NOD2 Protein, NOD2B, PSORAS1), Nod2 (Nucleotide Binding Oligomerization Domain 2 |
| known also as: |
ACUG, Arthrocutaneouveal Granulomatosis, BLAU, CARD15, CD, Caspase Recruitment Domain 15, IBD1, Inflammatory Bowel Disease Protein 1, LRR Containing Protein, NOD2 Protein, NOD2B, PSORAS1), Nod2 (Nucleotide Binding Oligomerization Domain 2 |
| known also as: |
Nod2 |
| known also as: |
ACUG, Arthrocutaneouveal Granulomatosis, BLAU, CARD15, CD, Caspase Recruitment Domain 15, IBD1, Inflammatory Bowel Disease Protein 1, LRR Containing Protein, NOD2 Protein, NOD2B, PSORAS1), Anti -Nod2 (Nucleotide Binding Oligomerization Domain 2 |
| Other names: |
CARD domain containing 2, N/A, NLR family, NOD-like receptor C2, NOD2 protein, OTTHUMP00000164224, OTTHUMP00000236088, caspase recruitment domain family, caspase recruitment domain protein 15, caspase recruitment domain-containing protein 15, inflammatory bowel disease protein 1, leucine rich repeat and CARD domain containing 2, member 15, nucleotide-binding oligomerization domain, nucleotide-binding oligomerization domain 2, nucleotide-binding oligomerization domain containing 2, nucleotide-binding oligomerization domain-containing protein 2, NOD2 |
| Other gene names: |
ACUG, BLAU, CARD15, CARD15, CD, CLR16, IBD1, N/A, NLRC2, NOD2B, PSORAS1, 3, NOD2 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Monkey, Human |
| Specificity and cross-reactivity: |
Other species have not been tested, Species Crossreactivity: This antibody reacts with human protein, The immunogen used for this antibody production has 100% homology with human and monkey protein, Specific for NOD2 protein |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
Tris-glycine buffer containing 150mM NaCl |
| Storage and shipping: |
Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
ACUG, Arthrocutaneouveal Granulomatosis, BLAU, CARD15, CD, Caspase Recruitment Domain 15, IBD1, Inflammatory Bowel Disease Protein 1, LRR Protein, NOD2 Protein, NOD2B, PSORAS1), Nod2 (Nucleotide Binding Oligomerization Domain 2 |
| Short name: |
ACUG, Arthrocutaneouveal Granulomatosis, BLAU, CARD15, CD, Caspase Recruitment Domain 15, IBD1, Inflammatory Bowel Disease Protein 1, LRR Protein, NOD2 Protein, NOD2B, PSORAS1) Antibody, Nod2 (Nucleotide Binding Oligomerization Domain 2 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ACUG, Arthrocutaneouveal Granulomatosis, BLAU, CARD15, CD, IBD1, Inflammatory Bowel Disease Protein 1, LRR Containing Protein, NOD2B, PSORAS1) (Antibody to), caspase Recruitment Domain 15, nucleotide-binding oli this GO merization domain containing 2 Protein, nucleotide-binding oli this GO merization domain containing 2 (Nucleotide Binding Oligomerization Domain 2 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CARD domain binding, Cell surfaces, NOD2 and IDBG-30654 and ENSG00000167207 and 64127, NOD2 and IDBG-631640 and ENSBTAG00000020936 and 444867, Nod2 and IDBG-179050 and ENSMUSG00000055994 and 257632, leucine rich repeat containing receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0042834 and peptidoglycan binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043234 and protein complex and cellular component this GO :0043330 and response to exogenous dsRNA and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0045087 and innate immune response and biological process this GO :0045089 and positive regulation of innate immune response and biological process this GO :0045747 and positive regulation of Notch signaling pathway and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046645 and positive regulation of gamma-delta T cell activation and biological process this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050700 and CARD domain binding and molecular function this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050727 and regulation of inflammatory response and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050766 and positive regulation of pha this GO cytosis and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0050871 and positive regulation of B cell activation and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0051353 and positive regulation of oxidoreductase activity and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0051770 and positive regulation of nitric-oxide synthase biosynthetic process and biological process this GO :0060585 and positive regulation of prostaglandin-endoperoxide synthase activity and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0070431 and nucleotide-binding oli this GO merization domain containing 2 signaling pathway and biological process this GO :0071224 and cellular response to peptidoglycan and biological process this GO :0071225 and cellular response to muramyl dipeptide and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071608 and macrophage inflammatory protein-1 alpha production and biological process this GO :0090022 and regulation of neutrophil chemotaxis and biological process this GO :2000110 and negative regulation of macrophage apoptotic process and biological process this GO :2000363 and positive regulation of prostaglandin-E synthase activity and biological process, this GO :0000187 and activation of MAPK activity and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002227 and innate immune response in mucosa and biological process this GO :0002253 and activation of immune response and biological process this GO :0002367 and cytokine production involved in immune response and biological process this GO :0002381 and immunoglobulin production involved in immunoglobulin mediated immune response and biological process this GO :0002606 and positive regulation of dendritic cell antigen processing and presentation and biological process this GO :0002710 and negative regulation of T cell mediated immunity and biological process this GO :0002732 and positive regulation of dendritic cell cytokine production and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0002830 and positive regulation of type 2 immune response and biological process this GO :0002862 and negative regulation of inflammatory response to antigenic stimulus and biological process this GO :0002925 and positive regulation of humoral immune response mediated by circulating immunoglobulin and biological process this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006952 and defense response and biological process this GO :0006963 and positive regulation of antibacterial peptide biosynthetic process and biological process this GO :0006965 and positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria and biological process this GO :0007254 and JNK cascade and biological process this GO :0007584 and response to nutrient and biological process this GO :0008180 and COP9 signalosome and cellular component this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009595 and detection of biotic stimulus and biological process this GO :0009986 and cell surface and cellular component this GO :0016045 and detection of bacterium and biological process this GO :0019899 and enzyme binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030277 and maintenance of gastrointestinal epithelium and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031982 and vesicle and cellular component this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032494 and response to peptidoglycan and biological process this GO :0032495 and response to muramyl dipeptide and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032498 and detection of muramyl dipeptide and biological process this GO :0032500 and muramyl dipeptide binding and molecular function this GO :0032689 and negative regulation of interferon-gamma production and biological process this GO :0032695 and negative regulation of interleukin-12 production and biological process this GO :0032701 and negative regulation of interleukin-18 production and biological process this GO :0032703 and negative regulation of interleukin-2 production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0032731 and positive regulation of interleukin-1 beta production and biological process this GO :0032733 and positive regulation of interleukin-10 production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032740 and positive regulation of interleukin-17 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0032874 and positive regulation of stress-activated MAPK cascade and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034136 and negative regulation of toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035419 and activation of MAPK activity involved in innate immune response and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035872 and nucleotide-binding domain, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0019899 : enzyme binding and also this GO :0019901 : protein kinase binding and also this GO :0032500 : muramyl dipeptide binding and also this GO :0042834 : peptidoglycan binding and also this GO :0050700 : CARD domain binding, this GO :0005524 : ATP binding, this GO :0019899 : enzyme binding, this GO :0019901 : protein kinase binding, this GO :0032500 : muramyl dipeptide binding, this GO :0042834 : peptidoglycan binding, this GO :0050700 : CARD domain binding, nucleotide-binding oli this GO merization domain containing 2 |
| Identity: |
5331 |
| Gene: |
NOD2 |
More about : NOD2 |
| Long gene name: |
nucleotide binding oligomerization domain containing 2 |
| Synonyms gene: |
IBD1 CARD15 |
| Synonyms gene name: |
caspase recruitment domain family, member 15 |
| Synonyms: |
BLAU CD PSORAS1 CLR16, 3 NLRC2 |
| Synonyms name: |
CARD domain containing 2 , leucine rich repeat and CARD domain containing 2 NOD-like receptor C2 NLR family, nucleotide-binding oligomerization domain |
| Locus: |
16q12, 1 |
| Discovery year: |
1998-07-10 |
| GenBank acession: |
AF178930 |
| Entrez gene record: |
64127 |
| Pubmed identfication: |
7809109 8587604 |
| RefSeq identity: |
NM_022162 |
| Classification: |
Caspase recruitment domain containing NLR family |
| Havana BLAST/BLAT: |
OTTHUMG00000133171 |
| Locus Specific Databases: |
LRG_177 |